Gene Symbol | Lamp1 |
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Entrez Gene | 16783 |
Alt Symbol | AI196048, CD107a, Lamp-1 |
Species | Mouse |
Gene Type | protein-coding |
Description | lysosomal-associated membrane protein 1 |
Other Description | 120 kDa lysosomal membrane glycoprotein|CD107 antigen-like family member A|LGP-120|LGP-A|LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B)|Lamp I|P2B|lysosomal membrane glycoprotein 1|lysosomal membrane glycoprotein A|lysosome-associated membrane glycoprotein 1|lysosome-associated membrane protein 1 |
Swissprots | P11438 Q62020 |
Accessions | EDL22121 EDL22122 EDL22123 P11438 AA154440 AI120997 AK004637 BAB23428 AK159096 BAE34812 AK159376 BAE35032 AK172007 BAE42773 AK178587 AK179610 AK179894 AK180006 AK181514 AK181607 AK182384 AK183572 AK183713 AK184936 AK185571 AK186339 AK186457 AK186523 AK187329 AK187750 AK191738 AK195229 AK200388 AK205762 AK206801 AK208324 AK208462 AK210006 AK212961 AK213434 AK214647 AK214981 AK215533 AK219163 AY069968 AAL58070 BC006044 BC006785 AAH06785 BC049097 AAH49097 J03881 AAA39411 M25244 AAA39869 M32015 AAA39428 XM_011242038 XP_011240340 NM_010684 NP_034814 |
Function | Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome {ECO:0000250}. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane. Colocalizes with OSBPL1A at the late endosome (By similarity). {ECO:0000250}. |
Top Pathways | Lysosome, Phagosome, Tuberculosis |
LAMP-1 CRISPR/Cas9 KO Plasmid (m) - sc-421382 from Santa Cruz Biotechnology
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LAMP-1 HDR Plasmid (m) - sc-421382-HDR from Santa Cruz Biotechnology
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LAMP-1 Double Nickase Plasmid (m) - sc-421382-NIC from Santa Cruz Biotechnology
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LAMP-1 Double Nickase Plasmid (m2) - sc-421382-NIC-2 from Santa Cruz Biotechnology
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LAMP-1 CRISPR Activation Plasmid (m) - sc-421382-ACT from Santa Cruz Biotechnology
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LAMP-1 CRISPR Activation Plasmid (m2) - sc-421382-ACT-2 from Santa Cruz Biotechnology
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LAMP-1 Lentiviral Activation Particles (m) - sc-421382-LAC from Santa Cruz Biotechnology
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LAMP-1 Lentiviral Activation Particles (m2) - sc-421382-LAC-2 from Santa Cruz Biotechnology
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LAMP-1 siRNA (m) - sc-35790 from Santa Cruz Biotechnology
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LAMP-1 shRNA Plasmid (m) - sc-35790-SH from Santa Cruz Biotechnology
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LAMP-1 shRNA (m) Lentiviral Particles - sc-35790-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU015631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN34605 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34605 from Sigma-Aldrich
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LAMP1 siRNA (Mouse) - CRM2300 from Cohesion Biosciences
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shRNA set against Mouse LAMP1 (NM_010684.2) - SHH328339 from Creative biogene
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shRNA set against Mouse Lamp1(NM_010684.2) - SHH141779 from Creative biogene
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Mouse LAMP1 siRNA - orb281776 from Biorbyt
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LAMP1 shRNA Plasmid (Mouse) - CHM2300 from Cohesion Biosciences
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LAMP1 miRNA 3'UTR clone - MiUTR1M-06518 from Creative biogene
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