Gene Symbol | MKL2 |
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Entrez Gene | 57496 |
Alt Symbol | MRTF-B, MRTFB, NPD001 |
Species | Human |
Gene Type | protein-coding |
Description | MKL/myocardin-like 2 |
Other Description | MKL/myocardin-like protein 2|megakaryoblastic leukemia 2|myocardin-related transcription factor B |
Swissprots | Q68CT1 B4DGT8 Q6UB16 Q8N226 Q86WW2 A6ND53 Q9ULH7 |
Accessions | EAW85112 EAW85113 EAW85114 EAW85115 Q9ULH7 AB033069 BAA86557 AF078853 AAD44485 AI498641 AK056385 AK057216 AK093577 BAC04200 AK126948 AK127530 BAG54517 AK294765 BAG57899 AY374297 AAQ82435 BC006977 BC016293 BC020644 BC030510 BC034934 AAH34934 BC038834 BC047761 AAH47761 BC050541 BC067270 BC073950 BC107868 BC127941 AAI27942 BC136260 AAI36261 BC171750 AAI71750 BX641041 CR749797 CAH18657 DB114294 XM_005255451 XP_005255508 XM_005255452 XP_005255509 XM_005255453 XP_005255510 XM_005255455 XP_005255512 XM_006720908 XP_006720971 XM_006720909 XP_006720972 XM_006720912 XP_006720975 XM_006720913 XP_006720976 XM_006720914 XP_006720977 XM_011522568 XP_011520870 XM_011522569 XP_011520871 NM_001308142 NP_001295071 NM_014048 NP_054767 |
Function | Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation. {ECO:0000269|PubMed:14565952}. |
Subcellular Location | Nucleus {ECO:0000250}. |
MRTF-B CRISPR/Cas9 KO Plasmid (h) - sc-401793 from Santa Cruz Biotechnology
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MRTF-B HDR Plasmid (h) - sc-401793-HDR from Santa Cruz Biotechnology
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MRTF-B Double Nickase Plasmid (h) - sc-401793-NIC from Santa Cruz Biotechnology
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MRTF-B Double Nickase Plasmid (h2) - sc-401793-NIC-2 from Santa Cruz Biotechnology
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MRTF-B CRISPR Activation Plasmid (h) - sc-401793-ACT from Santa Cruz Biotechnology
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MRTF-B CRISPR Activation Plasmid (h2) - sc-401793-ACT-2 from Santa Cruz Biotechnology
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MRTF-B Lentiviral Activation Particles (h) - sc-401793-LAC from Santa Cruz Biotechnology
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MRTF-B Lentiviral Activation Particles (h2) - sc-401793-LAC-2 from Santa Cruz Biotechnology
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MRTF-B siRNA (h) - sc-61074 from Santa Cruz Biotechnology
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MRTF-B shRNA Plasmid (h) - sc-61074-SH from Santa Cruz Biotechnology
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MRTF-B shRNA (h) Lentiviral Particles - sc-61074-V from Santa Cruz Biotechnology
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MKL2 RNAi - H00057496-R01 from Novus Biologicals
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MISSION® esiRNA - EHU067321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14379 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14379 from Sigma-Aldrich
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MKL2 siRNA (Human) - CRJ1485 from Cohesion Biosciences
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shRNA set against Human MKL2 (NM_014048.3) - SHH342288 from Creative biogene
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Human MKL2 siRNA - orb271986 from Biorbyt
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MKL2 shRNA Plasmid (Human) - CHJ1485 from Cohesion Biosciences
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MKL2 miRNA 3'UTR clone - MiUTR1H-06313 from Creative biogene
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