Gene Symbol |
ZSCAN4
|
Entrez Gene |
201516
|
Alt Symbol |
ZNF494
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
zinc finger and SCAN domain containing 4
|
Other Description |
zinc finger and SCAN domain-containing protein 4|zinc finger protein 494
|
Swissprots |
Q3MIQ2 Q8NAM6
|
Accessions |
EAW72523 Q8NAM6 AK092424 BAC03886 BC101738 AAI01739 BC101740 AAI01741 BX118882 EU446682 ABZ92211 XM_011526607 XP_011524909 XM_011526608 XP_011524910 XM_011526609 XP_011524911 NM_152677 NP_689890
|
Function |
Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00187}. Chromosome, telomere {ECO:0000250}.
|