Gene Symbol | KCNV2 |
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Entrez Gene | 169522 |
Alt Symbol | KV11.1, Kv8.2, RCD3B |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated modifier subfamily V, member 2 |
Other Description | potassium channel, subfamily V, member 2|potassium voltage-gated channel subfamily V member 2|voltage-gated potassium channel subunit Kv8.2 |
Swissprots | Q8TDN2 Q5T6X0 |
Accessions | EAW58803 Q8TDN2 AF348983 AAL83910 AK302215 BAG63572 BC101352 AAI01353 BC101353 AAI01354 BQ638061 EL952823 XR_929202 XR_929203 NM_133497 NP_598004 |
Function | Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1. |
Tissue Specificity | Detected in lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary and colon. {ECO:0000269|PubMed:12060745}. |
KCNV2 CRISPR/Cas9 KO Plasmid (h) - sc-409388 from Santa Cruz Biotechnology
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KCNV2 HDR Plasmid (h) - sc-409388-HDR from Santa Cruz Biotechnology
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KCNV2 Double Nickase Plasmid (h) - sc-409388-NIC from Santa Cruz Biotechnology
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KCNV2 Double Nickase Plasmid (h2) - sc-409388-NIC-2 from Santa Cruz Biotechnology
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KCNV2 CRISPR Activation Plasmid (h) - sc-409388-ACT from Santa Cruz Biotechnology
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KCNV2 CRISPR Activation Plasmid (h2) - sc-409388-ACT-2 from Santa Cruz Biotechnology
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KCNV2 Lentiviral Activation Particles (h) - sc-409388-LAC from Santa Cruz Biotechnology
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KCNV2 Lentiviral Activation Particles (h2) - sc-409388-LAC-2 from Santa Cruz Biotechnology
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KCNV2 siRNA (h) - sc-92827 from Santa Cruz Biotechnology
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KCNV2 shRNA Plasmid (h) - sc-92827-SH from Santa Cruz Biotechnology
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KCNV2 shRNA (h) Lentiviral Particles - sc-92827-V from Santa Cruz Biotechnology
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Kv8.2 RNAi - H00169522-R01 from Novus Biologicals
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MISSION® esiRNA - EHU137041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2528 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2528 from Sigma-Aldrich
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KCNV2 siRNA (Human) - CRJ6088 from Cohesion Biosciences
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shRNA set against Human KCNV2 (NM_133497.3) - SHH323795 from Creative biogene
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KCNV2 shRNA Plasmid (Human) - CHJ6088 from Cohesion Biosciences
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KCNV2 miRNA 3'UTR clone - MiUTR4H-TG04734 from Creative biogene
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