| Gene Symbol |
CNTROB
|
| Entrez Gene |
116840
|
| Alt Symbol |
LIP8, PP1221
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
centrobin, centrosomal BRCA2 interacting protein
|
| Other Description |
LYST-interacting protein 8|LYST-interacting protein LIP8|centrobin|centrosomal BRCA2-interacting protein
|
| Swissprots |
Q96CQ7 Q8WXV3 Q8NCB8 A6NHQ1 Q8N137 Q9C060 Q331K3 Q69YV7
|
| Accessions |
EAW90104 EAW90105 EAW90106 EAW90107 EAW90108 Q8N137 AF141344 AAG49447 AF331638 AAL56068 AI494457 AK074847 BAC11241 AK293076 BAF85765 AK303093 BAG64203 AL833907 CAD38763 AY160226 AAO22135 AY160227 AAO22136 BC014055 AAH14055 BC021134 AAH21134 CN390730 DQ892038 ABM82964 DQ895229 ABM86155 XM_005256437 XP_005256494 XM_005256438 XP_005256495 XM_005256439 XP_005256496 XM_006721438 XP_006721501 XM_006721439 XP_006721502 XM_006721440 XP_006721503 XM_011523634 XP_011521936 XM_011523635 XP_011521937 XM_011523636 XP_011521938 XM_011523637 XP_011521939 NM_001037144 NP_001032221 NM_053051 NP_444279
|
| Function |
Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis. {ECO:0000269|PubMed:16275750}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:16275750}. Note=Centriole-associated, asymmetrically localizes to the daughter centriole.
|
| Tissue Specificity |
Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:16275750}.
|