| Gene Symbol |
Cradd
|
| Entrez Gene |
12905
|
| Alt Symbol |
RAIDD
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
CASP2 and RIPK1 domain containing adaptor with death domain
|
| Other Description |
CASP2 and RIPK1 domain-containing adaptor with death domain|RIP-associated protein with a death domain|caspase and RIP adapter with death domain|death domain-containing protein CRADD
|
| Swissprots |
Q9QUN0 O88843
|
| Accessions |
AAN84619 EDL21592 EDL21593 EDL21594 EDL21595 EDL21596 O88843 AF017992 AAC35882 AJ224738 CAA12107 AJ224739 CAA12108 AJ224740 CAA12109 AK052304 AK131713 BAE20775 AK136561 BAE23045 AK144648 BAE25988 AK163112 BAE37198 BC005608 AAH05608 XM_006513178 XP_006513241 XM_006513179 XP_006513242 XM_006513180 XP_006513243 XM_006513181 XP_006513244 XM_006513182 XP_006513245 XM_006513183 XP_006513246 XM_006513184 XP_006513247 NM_009950 NP_034080
|
| Function |
Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:22279524}. Nucleus {ECO:0000269|PubMed:22279524}.
|