Gene Symbol | DENND4B |
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Entrez Gene | 9909 |
Alt Symbol | KIAA0476 |
Species | Human |
Gene Type | protein-coding |
Description | DENN/MADD domain containing 4B |
Other Description | DENN domain-containing protein 4B |
Swissprots | O75064 Q5T4K0 |
Accessions | EAW53268 EAW53269 O75064 AB007945 BAA32321 AK124049 AK129713 AK226053 AL512734 BC167792 AAI67792 L10375 XM_005245678 XP_005245735 XM_005245679 XP_005245736 XM_011510219 XP_011508521 XM_011510220 XP_011508522 XM_011510221 XP_011508523 XM_011510222 XP_011508524 XR_426806 NM_014856 NP_055671 |
Function | Guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. {ECO:0000269|PubMed:20937701}. |
Subcellular Location | Golgi apparatus {ECO:0000269|PubMed:20937701}. |
DENND4B CRISPR/Cas9 KO Plasmid (h) - sc-411384 from Santa Cruz Biotechnology
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DENND4B HDR Plasmid (h) - sc-411384-HDR from Santa Cruz Biotechnology
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DENND4B Double Nickase Plasmid (h) - sc-411384-NIC from Santa Cruz Biotechnology
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DENND4B Double Nickase Plasmid (h2) - sc-411384-NIC-2 from Santa Cruz Biotechnology
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DENND4B CRISPR Activation Plasmid (h) - sc-411384-ACT from Santa Cruz Biotechnology
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DENND4B CRISPR Activation Plasmid (h2) - sc-411384-ACT-2 from Santa Cruz Biotechnology
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DENND4B Lentiviral Activation Particles (h) - sc-411384-LAC from Santa Cruz Biotechnology
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DENND4B Lentiviral Activation Particles (h2) - sc-411384-LAC-2 from Santa Cruz Biotechnology
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DENND4B siRNA (h) - sc-88449 from Santa Cruz Biotechnology
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DENND4B shRNA Plasmid (h) - sc-88449-SH from Santa Cruz Biotechnology
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DENND4B shRNA (h) Lentiviral Particles - sc-88449-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU102071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7143 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7143 from Sigma-Aldrich
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DENND4B siRNA (Human) - CRH6654 from Cohesion Biosciences
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DENND4B - MBS8215040 from MyBioSource
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Human DENND4B siRNA - orb267156 from Biorbyt
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DENND4B shRNA Plasmid (Human) - CHH6654 from Cohesion Biosciences
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DENND4B miRNA 3'UTR clone - MiUTR3H-14640 from Creative biogene
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