| Gene Symbol |
B4GALT7
|
| Entrez Gene |
11285
|
| Alt Symbol |
EDSP1, XGALT1, XGPT1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
|
| Other Description |
UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7|UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7|beta-1,4-GalTase 7|beta-1,4-galactosyltransferase 7|beta-1,4-galactosyltransferase VII|beta4Gal-T7|beta4GalT-VII|galactosyltransferase I|proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I
|
| Swissprots |
B3KN39 Q9UHN2 Q9UBV7
|
| Accessions |
CAE90482 CAM55968 EAW84964 EAW84965 Q9UBV7 AB028600 BAA83414 AF142675 AAF22225 AJ005382 CAB56424 AK022566 BAG51093 AK023506 BAG51201 AK095882 BAG53157 AK123092 AY358578 AAQ88941 BC007317 AAH07317 BC062983 AAH62983 BC072403 AAH72403 DQ893010 ABM83936 DQ896256 ABM87255 XM_005265805 XP_005265862 XM_006714816 XP_006714879 XM_011534421 XP_011532723 NM_007255 NP_009186
|
| Function |
Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts. {ECO:0000269|PubMed:24052259}.
|
| Subcellular Location |
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Cis cisternae of Golgi stack.
|
| Tissue Specificity |
High expression in heart, pancreas and liver, medium in placenta and kidney, low in brain, skeletal muscle and lung.
|
| Top Pathways |
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin
|