| Gene Symbol |
MED9
|
| Entrez Gene |
55090
|
| Alt Symbol |
MED25
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 9
|
| Other Description |
mediator of RNA polymerase II transcription subunit 9|mediator of RNA polymerase II transcription, subunit 9 homolog|mediator subunit 25
|
| Swissprots |
Q9NWA0
|
| Accessions |
EAW55706 EAW55707 Q9NWA0 AK001055 BAA91483 BC000647 BC010906 BC104988 AAI04989 BC112029 AAI12030 HG518168 CDI06891 NM_018019 NP_060489
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
![Western Blot: MED9 Overexpression Lysate (Adult Normal) [NBL1-12997] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MED9.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7458_MED9%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12997-img0002.jpg)