| Gene Symbol |
FAM213A
|
| Entrez Gene |
84293
|
| Alt Symbol |
C10orf58, PAMM
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
family with sequence similarity 213, member A
|
| Other Description |
UPF0765 protein C10orf58|peroxiredoxin (PRX)-like 2 activated in M-CSF stimulated monocytes|peroxiredoxin-like 2 activated in M-CSF stimulated monocytes|redox-regulatory protein FAM213A|redox-regulatory protein PAMM
|
| Swissprots |
Q8NBK9 Q96JR0 Q8N2K3 Q6UW08 B2RD81 Q9BRX8
|
| Accessions |
CAF85885 CAI93500 Q9BRX8 AA829725 AF086462 AF305824 AAK55527 AI589570 AK022598 AK027858 AK074643 BAC11108 AK075447 BAC11627 AK126292 AK225387 AK315440 BAG37828 AY359059 AAQ89418 BC005871 AAH05871 BC024308 BC045777 BC071938 BE742158 CN396006 DA136257 DB494833 DB532554 XM_011540264 XP_011538566 XM_011540265 XP_011538567 XM_011540266 XP_011538568 NM_001243778 NP_001230707 NM_001243779 NP_001230708 NM_001243780 NP_001230709 NM_001243781 NP_001230710 NM_001243782 NP_001230711 NM_032333 NP_115709
|
| Function |
Involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. {ECO:0000269|PubMed:19951071}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19951071}.
|
| Tissue Specificity |
Expressed in CSF1 and TNFSF11-stimulated CD14(+) peripheral blood mononuclear cells (PBMCs). {ECO:0000269|PubMed:19951071}.
|