Gene Symbol | BAHD1 |
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Entrez Gene | 22893 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | bromo adjacent homology domain containing 1 |
Other Description | BAH domain-containing protein 1|bromo adjacent homology domain-containing 1 protein |
Swissprots | Q8TBE0 Q8NDF7 Q9Y2F4 |
Accessions | EAW92416 EAW92417 EAW92418 Q8TBE0 AB023162 BAA76789 AL833923 CAD38779 BC022782 AAH22782 BU740533 HY041603 HY353002 JF432274 ADZ15491 XM_011521366 XP_011519668 XM_011521367 XP_011519669 XM_011521368 XP_011519670 XM_011521369 XP_011519671 NM_001301132 NP_001288061 NM_014952 NP_055767 NR_125372 |
Function | Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins. At specific stages of Listeria infection, in complex with TRIM28, corepresses interferon- stimulated genes, including IFNL1, IFNL2 and IFNL3. {ECO:0000269|PubMed:19666599, ECO:0000269|PubMed:21252314}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19666599}. Chromosome {ECO:0000269|PubMed:19666599}. Note=Localizes to heterochromatin and inactive X chromosome. Colocalizes with histone H3 trimethylated at 'Lys-27' (H3K27me3). |
BAHD1 CRISPR/Cas9 KO Plasmid (h) - sc-409825 from Santa Cruz Biotechnology
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BAHD1 HDR Plasmid (h) - sc-409825-HDR from Santa Cruz Biotechnology
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BAHD1 Double Nickase Plasmid (h) - sc-409825-NIC from Santa Cruz Biotechnology
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BAHD1 Double Nickase Plasmid (h2) - sc-409825-NIC-2 from Santa Cruz Biotechnology
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BAHD1 CRISPR Activation Plasmid (h) - sc-409825-ACT from Santa Cruz Biotechnology
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BAHD1 CRISPR Activation Plasmid (h2) - sc-409825-ACT-2 from Santa Cruz Biotechnology
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BAHD1 Lentiviral Activation Particles (h) - sc-409825-LAC from Santa Cruz Biotechnology
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BAHD1 Lentiviral Activation Particles (h2) - sc-409825-LAC-2 from Santa Cruz Biotechnology
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BAHD1 siRNA (h) - sc-90189 from Santa Cruz Biotechnology
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BAHD1 shRNA Plasmid (h) - sc-90189-SH from Santa Cruz Biotechnology
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BAHD1 shRNA (h) Lentiviral Particles - sc-90189-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU013091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3847 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3847 from Sigma-Aldrich
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BAHD1 siRNA (Human) - CRH7849 from Cohesion Biosciences
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BAHD1 RNAi - H00022893-R01 from Novus Biologicals
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BAHD1 - MBS8206096 from MyBioSource
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shRNA set against Human BAHD1 (NM_014952.3) - SHH244702 from Creative biogene
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shRNA set against Human BAHD1(NM_014952.3) - SHG090631 from Creative biogene
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BAHD1 shRNA Plasmid (Human) - CHH7849 from Cohesion Biosciences
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BAHD1 miRNA 3'UTR clone - MiUTR1H-00794 from Creative biogene
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