| Gene Symbol |
UBXN2B
|
| Entrez Gene |
137886
|
| Alt Symbol |
p37
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UBX domain protein 2B
|
| Other Description |
NSFL1 cofactor p37|UBX domain-containing protein 2B|p97 cofactor p37
|
| Swissprots |
B3KWZ3 Q14CS0
|
| Accessions |
Q14CS0 AK054658 AK091561 AK126300 BAG54305 AL831990 AL833075 BC113645 AAI13646 BX647876 HQ258392 ADR83146 U79282 XM_005251165 XP_005251222 XM_005251166 XP_005251223 XR_242453 NM_001077619 NP_001071087
|
| Function |
Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. {ECO:0000269|PubMed:17141156}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}.
|
![Western Blot: UBXN2B Overexpression Lysate (Adult Normal) [NBP2-08463] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for UBXN2B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9451_UBXN2B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08463-img0001.jpg)