| Gene Symbol |
IL10RA
|
| Entrez Gene |
3587
|
| Alt Symbol |
CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interleukin 10 receptor, alpha
|
| Other Description |
IL-10 receptor subunit alpha|IL-10R subunit 1|IL-10R subunit alpha|IL-10RA|interleukin-10 receptor alpha chain|interleukin-10 receptor subunit 1|interleukin-10 receptor subunit alpha
|
| Swissprots |
Q13651 A8K6I0 B0YJ27
|
| Accessions |
AAN86349 ACA06005 EAW67343 Q13651 AB209626 BAD92863 AK291645 BAF84334 AK301260 BAG62826 AK301484 BAG62998 AK301492 BAG63003 AK313049 AK316146 BAH14517 AK316342 BAH14713 BC028082 AAH28082 BM193545 CA307153 DQ891031 ABM81957 DQ893720 ABM84646 JN591377 AEX60806 U00672 AAA17896 NM_001558 NP_001549 NR_026691
|
| Function |
Receptor for IL10; binds IL10 with a high affinity.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Toxoplasmosis, Tuberculosis, Epstein-Barr virus infection
|
![Western Blot: IL10RA Overexpression Lysate (Adult Normal) [NBL1-11896] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IL10RA.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26232_IL10RA%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11896-img0002.jpg)