SERPINB4

Gene Symbol	SERPINB4
Entrez Gene	6318
Alt Symbol	LEUPIN, PI11, SCCA-2, SCCA1, SCCA2
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade B (ovalbumin), member 4
Other Description	SCCA2/SCCA1 fusion protein\|peptidase inhibitor 11\|protease inhibitor (leucine-serpin)\|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4\|serpin B4\|squamous cell carcinoma antigen 1\|squamous cell carcinoma antigen 2
Swissprots	A8K847 P48594
Accessions	AAA92602 BAA75462 BAB21525 EAW63154 EAW63155 P48594 AB046400 BAB40773 AF461147 AAQ04771 AK292212 BAF84901 AY245780 AAO92271 AY245782 AAO92273 BC008399 BC017401 AAH17401 BU676816 DB118691 DQ892794 ABM83720 DQ896041 ABM87040 U19557 AAA97553 X89015 CAA61420 XM_011526138 XP_011524440 NM_002974 NP_002965 NM_175041 NP_778206
Function	May act as a protease inhibitor to modulate the host immune response against tumor cells.
Subcellular Location	Cytoplasm {ECO:0000269\|PubMed:10956412}. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
Tissue Specificity	Squamous cells.
Top Pathways	Amoebiasis

SCCA1/2 (B-9) - sc-28384 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

SCCA1/2 (B-9): sc-28384. Western blot analysis of SCCA1/2 expression in A-431 whole cell lysate.

SCCA1/2 (FL-390) - sc-25741 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

SCCA1/2 (FL-390): sc-25741. Western blot analysis of SCCA1/2 expression in SCC-4 (A) and A-431 (B) whole cell lysates.

SCCA2 (39) - sc-130343 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

SCCA2 (39): sc-130343. Western blot analysis of human recombinant SCCA2.

SCCA2 (10C12) - sc-21793 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

SCCA2 (10C12): sc-21793. Immunoperoxidase staining of paraffin-embedded human psoratic skin tissue. Kindly provided by Dr. Gary Silverman of Childrens Hospital, Boston.

SCCA2 (64) - sc-130342 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

SCCA2 (64): sc-130342. Western blot analysis of human recombinant SCCA2.

Anti-SERPINB4 antibody - ab197096 from Abcam

Prices	$370.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human fetal pancreas tissue labeling SERPINB4 with ab197096 at 1/100 dilution.

Anti-SERPINB4 antibody - ab104338 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SERPINB4 antibody (ab104338) at 1 µg/ml + HepG2 cell lysate at 10 µg

Anti-SERPINB4 antibody - ab138046 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SERPINB4 antibody (ab138046) at 1/500 dilution + COLO205 cell lysate at 30 µg

Anti-SERPINB4 antibody [2B9] - ab117953 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2B9

All lanes : Anti-SERPINB4 antibody [2B9] (ab117953) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY SERPINB4 cDNALysates/proteins at 5 µg per lane.

Anti-SERPINB4 antibody [39] - ab88338 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	39

Anti-SERPINB4 / SCCA1+2 Antibody - LS-C137570 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal

Anti-SERPINB4 / SCCA1+2 Antibody - LS-C137571 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal

Anti-SERPINB4 / SCCA1+2 Antibody - LS-C137572 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal

Anti-SERPINB4 / SCCA1+2 Antibody (aa35-84) - LS-C116199 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

SERPINB4 / SCCA1 antibody LS-C116199 Western blot of HepG2 cell lysate.

Anti-SERPINB4 / SCCA1+2 Antibody (aa275-304, AP) - LS-C270127 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SERPINB4 / SCCA1+2 Antibody (aa275-304, APC) - LS-C270128 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SERPINB4 / SCCA1+2 Antibody (aa246-295) - LS-C200656 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of the lysates from COLO205 cells using SERPINB4 antibody.

Anti-SERPINB4 / SCCA1+2 Antibody (clone 2H8) - LS-C172627 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2H8

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINB4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINB4.

Anti-SERPINB4 / SCCA1+2 Antibody (aa275-304, Biotin) - LS-C270129 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SERPINB4 / SCCA1+2 Antibody (aa275-304, FITC) - LS-C270130 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SERPINB4 / SCCA1+2 Antibody (clone 3C5) - LS-C172628 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	3C5

Anti-SERPINB4 / SCCA1+2 Antibody (aa275-304, Azide-free, HRP) - LS-C270131 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SERPINB4 / SCCA1+2 Antibody (aa275-304, PE) - LS-C270133 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SERPINB4 / SCCA1+2 Antibody (clone 1G6) - LS-C172629 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1G6

Anti-SERPINB4 / SCCA1+2 Antibody (aa261-310) - LS-C291387 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

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