Gene Symbol | EAF1 |
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Entrez Gene | 85403 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ELL associated factor 1 |
Other Description | ELL (eleven nineteen lysine-rich leukemia gene)-associated factor 1|ELL-associated factor 1 |
Swissprots | Q96JC9 B4E3F5 Q8IW10 |
Accessions | EAW64234 Q96JC9 AA626023 AF272973 AAK58687 AK023217 AK304697 BAG65467 AK312330 AL698790 AW292089 BC029294 BC035167 BC041329 AAH41329 BI459315 BM836669 BM918150 BQ064584 XM_005265518 XP_005265575 XM_011534165 XP_011532467 XM_011534166 XP_011532468 NM_033083 NP_149074 |
Function | Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. {ECO:0000269|PubMed:11418481, ECO:0000269|PubMed:16006523}. |
Subcellular Location | Nucleus speckle. Nucleus, Cajal body. Note=Colocalizes with ELL to nuclear speckles. Also localized to Cajal (coiled) bodies. |
Tissue Specificity | Strongly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine and colon. Poorly expressed in thymus. {ECO:0000269|PubMed:11418481}. |
EAF1 CRISPR/Cas9 KO Plasmid (h) - sc-410221 from Santa Cruz Biotechnology
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EAF1 HDR Plasmid (h) - sc-410221-HDR from Santa Cruz Biotechnology
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EAF1 Double Nickase Plasmid (h) - sc-410221-NIC from Santa Cruz Biotechnology
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EAF1 Double Nickase Plasmid (h2) - sc-410221-NIC-2 from Santa Cruz Biotechnology
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EAF1 CRISPR Activation Plasmid (h) - sc-410221-ACT from Santa Cruz Biotechnology
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EAF1 CRISPR Activation Plasmid (h2) - sc-410221-ACT-2 from Santa Cruz Biotechnology
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EAF1 Lentiviral Activation Particles (h) - sc-410221-LAC from Santa Cruz Biotechnology
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EAF1 Lentiviral Activation Particles (h2) - sc-410221-LAC-2 from Santa Cruz Biotechnology
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EAF1 siRNA (h) - sc-62249 from Santa Cruz Biotechnology
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EAF1 shRNA Plasmid (h) - sc-62249-SH from Santa Cruz Biotechnology
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EAF1 shRNA (h) Lentiviral Particles - sc-62249-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU106361 from Sigma-Aldrich
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MISSION® esiRNA - EHU012381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7612 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7612 from Sigma-Aldrich
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EAF1 siRNA (Human) - CRJ3797 from Cohesion Biosciences
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EAF1 - MBS8201038 from MyBioSource
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shRNA set against Human EAF1 (NM_033083.6) - SHH282621 from Creative biogene
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Human EAF1 siRNA - orb274298 from Biorbyt
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EAF1 shRNA Plasmid (Human) - CHJ3797 from Cohesion Biosciences
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EAF1 miRNA 3'UTR clone - MiUTR1H-03081 from Creative biogene
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