Gene Symbol | ACTN3 |
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Entrez Gene | 89 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | actinin, alpha 3 (gene/pseudogene) |
Other Description | F-actin cross-linking protein|alpha-actinin skeletal muscle|alpha-actinin-3 |
Swissprots | Q08043 Q4KKV2 A6NP77 |
Accessions | EAW74546 Q08043 AJ346025 AK125851 AK303044 BAG64164 AK313556 BAG36331 AL043389 BC096323 AAH96323 BC099647 AAH99647 BC099648 AAH99648 BC099649 AAH99649 BQ575174 BU732652 CX787471 DA827389 DA915904 M86407 AAA51585 NM_001104 NP_001095 NM_001258371 NP_001245300 NR_047663 |
Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
Tissue Specificity | Expressed only in a subset of type 2 skeletal muscle fibers. {ECO:0000269|PubMed:11440986}. |
Top Pathways | Systemic lupus erythematosus, Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Leukocyte transendothelial migration, Amoebiasis |
α-actinin-3 CRISPR/Cas9 KO Plasmid (h) - sc-401486 from Santa Cruz Biotechnology
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α-actinin-3 HDR Plasmid (h) - sc-401486-HDR from Santa Cruz Biotechnology
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α-actinin-3 Double Nickase Plasmid (h) - sc-401486-NIC from Santa Cruz Biotechnology
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α-actinin-3 Double Nickase Plasmid (h2) - sc-401486-NIC-2 from Santa Cruz Biotechnology
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α-actinin-3 CRISPR Activation Plasmid (h) - sc-401486-ACT from Santa Cruz Biotechnology
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α-actinin-3 CRISPR Activation Plasmid (h2) - sc-401486-ACT-2 from Santa Cruz Biotechnology
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α-actinin-3 Lentiviral Activation Particles (h) - sc-401486-LAC from Santa Cruz Biotechnology
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α-actinin-3 Lentiviral Activation Particles (h2) - sc-401486-LAC-2 from Santa Cruz Biotechnology
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α-actinin-3 siRNA (h) - sc-43099 from Santa Cruz Biotechnology
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α-actinin-3 shRNA Plasmid (h) - sc-43099-SH from Santa Cruz Biotechnology
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α-actinin-3 shRNA (h) Lentiviral Particles - sc-43099-V from Santa Cruz Biotechnology
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Alpha Actinin 3 RNAi - H00000089-R01 from Novus Biologicals
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MISSION® esiRNA - EHU142071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2781 from Sigma-Aldrich
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ACTN3 siRNA (Human) - CRH0055 from Cohesion Biosciences
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ACTN3 - MBS8233283 from MyBioSource
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shRNA set against Human ACTN3 (NM_001104.2) - SHH231054 from Creative biogene
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Human ACTN3 siRNA - orb260557 from Biorbyt
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ACTN3 shRNA Plasmid (Human) - CHH0055 from Cohesion Biosciences
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ACTN3 miRNA 3'UTR clone - MiUTR3H-00021 from Creative biogene
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