Gene Symbol | Aspa |
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Entrez Gene | 11484 |
Alt Symbol | Acy-2, Acy2, nur7 |
Species | Mouse |
Gene Type | protein-coding |
Description | aspartoacylase |
Other Description | aminoacylase-2|aspartoacylase (aminoacylase) 2 |
Swissprots | Q8R3P0 Q9JIN8 Q9D876 Q5SV07 Q9DCE2 |
Accessions | EDL12720 EDL12721 EDL12722 Q8R3P0 AF212998 AAF76459 AI527854 AK002859 BAB22412 AK008354 BAB25624 AK035910 BAC29240 BC024934 AAH24934 XM_006532010 XP_006532073 XM_006532011 XP_006532074 XM_006532012 XP_006532075 XM_006532013 XP_006532076 XM_006536285 XP_006536348 XM_006536286 XP_006536349 XM_006536287 XP_006536350 XM_006536288 XP_006536351 XM_011248672 XP_011246974 XM_011248673 XP_011246975 XM_011251198 XP_011249500 XM_011251199 XP_011249501 NM_023113 NP_075602 |
Function | Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Nucleus {ECO:0000250}. |
Top Pathways | Alanine, aspartate and glutamate metabolism, Histidine metabolism |
Aspartoacylase CRISPR/Cas9 KO Plasmid (m) - sc-418979 from Santa Cruz Biotechnology
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Aspartoacylase HDR Plasmid (m) - sc-418979-HDR from Santa Cruz Biotechnology
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Aspartoacylase Double Nickase Plasmid (m) - sc-418979-NIC from Santa Cruz Biotechnology
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Aspartoacylase Double Nickase Plasmid (m2) - sc-418979-NIC-2 from Santa Cruz Biotechnology
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Aspartoacylase CRISPR Activation Plasmid (m) - sc-418979-ACT from Santa Cruz Biotechnology
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Aspartoacylase CRISPR Activation Plasmid (m2) - sc-418979-ACT-2 from Santa Cruz Biotechnology
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Aspartoacylase Lentiviral Activation Particles (m) - sc-418979-LAC from Santa Cruz Biotechnology
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Aspartoacylase Lentiviral Activation Particles (m2) - sc-418979-LAC-2 from Santa Cruz Biotechnology
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Aspartoacylase siRNA (m) - sc-141303 from Santa Cruz Biotechnology
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Aspartoacylase shRNA Plasmid (m) - sc-141303-SH from Santa Cruz Biotechnology
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Aspartoacylase shRNA (m) Lentiviral Particles - sc-141303-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU061691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN27106 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27106 from Sigma-Aldrich
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ASPA siRNA (Mouse) - CRM0052 from Cohesion Biosciences
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ASPA - MBS8236674 from MyBioSource
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shRNA set against Mouse ASPA (NM_023113.4) - SHH241578 from Creative biogene
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shRNA set against Mouse Aspa(NM_023113.4) - SHG077947 from Creative biogene
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Mouse ASPA siRNA - orb279528 from Biorbyt
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ASPA shRNA Plasmid (Mouse) - CHM0052 from Cohesion Biosciences
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ASPA miRNA 3'UTR clone - MiUTR1M-01756 from Creative biogene
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