Gene Symbol |
LOC100328613
|
Entrez Gene |
100328613
|
Alt Symbol |
CYP1A1, CYPIA1
|
Species |
Rabbit
|
Gene Type |
protein-coding
|
Description |
polycyclic hydrocarbon-inducible cytochrome P450c
|
Other Description |
P-450 PHPAH1|P450 LM6|P450 isozyme 6|cytochrome P-450 PHPAH1|cytochrome P450 1A1|cytochrome P450 LM6|cytochrome P450 isozyme 6
|
Swissprots |
P05176
|
Accessions |
P05176 M11727 AAA31431 X05685 CAA29170 XM_008252400 XP_008250622 NM_001171072 NP_001164543
|
Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
|
Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
Top Pathways |
Steroid hormone biosynthesis, Chemical carcinogenesis, Ovarian steroidogenesis, Tryptophan metabolism, Retinol metabolism
|