HAVCR1
| Gene Symbol | HAVCR1 |
|---|---|
| Entrez Gene | 26762 |
| Alt Symbol | HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | hepatitis A virus cellular receptor 1 |
| Other Description | T cell immunoglobin domain and mucin domain protein 1|T-cell immunoglobulin mucin family member 1|T-cell immunoglobulin mucin receptor 1|T-cell membrane protein 1|kidney injury molecule 1 |
| Swissprots | O43656 Q96D42 |
| Accessions | BAJ61033 EAW61615 EAW61616 Q96D42 AF043724 AAC39862 AK298259 BAG60523 AW604297 BC013325 AAH13325 BG752287 CR457114 CAG33395 DA378449 DA384612 DQ892770 ABM83696 DQ896019 ABM87018 HQ412639 ADZ24772 HQ412640 ADZ24773 HQ412641 ADZ24774 JX049978 AFO66592 XM_006714840 XP_006714903 XM_011534507 XP_011532809 XM_011534508 XP_011532810 XM_011534509 XP_011532811 XM_011534510 XP_011532812 XM_011534511 XP_011532813 XM_011534512 XP_011532814 XM_011534513 XP_011532815 XM_011534514 XP_011532816 XM_011534515 XP_011532817 XR_941098 XR_941099 XR_941100 NM_001173393 NP_001166864 NM_001308156 NP_001295085 NM_012206 NP_036338 NM_001099414 NP_001092884 |
| Function | May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. {ECO:0000250, ECO:0000269|PubMed:17471468, ECO:0000269|PubMed:9658108}. |
| Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Tissue Specificity | Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses. {ECO:0000269|PubMed:9658108}. |
TIM-1 CRISPR/Cas9 KO Plasmid (h) - sc-411938 from Santa Cruz Biotechnology
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TIM-1 HDR Plasmid (h) - sc-411938-HDR from Santa Cruz Biotechnology
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TIM-1 Double Nickase Plasmid (h) - sc-411938-NIC from Santa Cruz Biotechnology
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TIM-1 Double Nickase Plasmid (h2) - sc-411938-NIC-2 from Santa Cruz Biotechnology
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TIM-1 CRISPR Activation Plasmid (h) - sc-411938-ACT from Santa Cruz Biotechnology
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TIM-1 CRISPR Activation Plasmid (h2) - sc-411938-ACT-2 from Santa Cruz Biotechnology
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TIM-1 Lentiviral Activation Particles (h) - sc-411938-LAC from Santa Cruz Biotechnology
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TIM-1 Lentiviral Activation Particles (h2) - sc-411938-LAC-2 from Santa Cruz Biotechnology
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TIM-1 siRNA (h) - sc-61691 from Santa Cruz Biotechnology
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TIM-1 shRNA Plasmid (h) - sc-61691-SH from Santa Cruz Biotechnology
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TIM-1 shRNA (h) Lentiviral Particles - sc-61691-V from Santa Cruz Biotechnology
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TIM-1/KIM-1/HAVCR RNAi - H00026762-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9888 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9888 from Sigma-Aldrich
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HAVCR1 siRNA (Human) - CRH8898 from Cohesion Biosciences
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TIM-1/KIM-1/HAVCR RNAi - H00026762-R01 from Novus Biologicals
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HAVCR1 - MBS8218731 from MyBioSource
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shRNA set against Human HAVCR1 (NM_012206.2) - SHH310505 from Creative biogene
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Human HAVCR1 siRNA - orb269400 from Biorbyt
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HAVCR1 shRNA Plasmid (Human) - CHH8898 from Cohesion Biosciences
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HAVCR1 miRNA 3'UTR clone - MiUTR1H-04381 from Creative biogene
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