Gene Symbol | MYO5A |
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Entrez Gene | 4644 |
Alt Symbol | GS1, MYH12, MYO5, MYR12 |
Species | Human |
Gene Type | protein-coding |
Description | myosin VA (heavy chain 12, myoxin) |
Other Description | dilute myosin heavy chain, non-muscle|myosin V|myosin, heavy polypeptide kinase|myosin-12|myosin-Va|myoxin|unconventional myosin-Va |
Swissprots | Q16249 Q9Y4I1 Q9UE31 Q9UE30 Q07902 O60653 A8MZC5 |
Accessions | EAW77447 EAW77448 EAW77449 EAW77450 EAW77451 EAW77452 EAW77453 Q9Y4I1 AB209487 BAD92724 AB209505 BAD92742 AB290180 BAF80583 AF055459 AAC14188 AF090424 AAC83701 AF090425 AAC83702 AF090426 AAC83703 AF090427 AAC83704 AF090428 AAC83705 AK090859 AK124898 AK303660 BAG64659 AK307600 BC156392 AAI56393 BC172485 AAI72485 BU738571 EU921839 ACH48182 S74799 AAB33211 U90942 AAD00702 Y07759 CAA69035 XM_005254397 XP_005254454 XM_005254398 XP_005254455 XM_011521606 XP_011519908 XM_011521607 XP_011519909 XM_011521608 XP_011519910 XM_011521609 XP_011519911 XM_011521610 XP_011519912 XM_011521611 XP_011519913 XM_011521612 XP_011519914 NM_000259 NP_000250 NM_001142495 NP_001135967 |
Function | Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation. {ECO:0000269|PubMed:10448864}. |
Tissue Specificity | Detected in melanocytes. |
Myosin Va CRISPR/Cas9 KO Plasmid (h) - sc-402108 from Santa Cruz Biotechnology
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Myosin Va HDR Plasmid (h) - sc-402108-HDR from Santa Cruz Biotechnology
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Myosin Va Double Nickase Plasmid (h) - sc-402108-NIC from Santa Cruz Biotechnology
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Myosin Va Double Nickase Plasmid (h2) - sc-402108-NIC-2 from Santa Cruz Biotechnology
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Myosin Va CRISPR Activation Plasmid (h) - sc-402108-ACT from Santa Cruz Biotechnology
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Myosin Va CRISPR Activation Plasmid (h2) - sc-402108-ACT-2 from Santa Cruz Biotechnology
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Myosin Va Lentiviral Activation Particles (h) - sc-402108-LAC from Santa Cruz Biotechnology
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Myosin Va Lentiviral Activation Particles (h2) - sc-402108-LAC-2 from Santa Cruz Biotechnology
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Myosin Va siRNA (h) - sc-35995 from Santa Cruz Biotechnology
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Myosin Va shRNA Plasmid (h) - sc-35995-SH from Santa Cruz Biotechnology
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Myosin Va shRNA (h) Lentiviral Particles - sc-35995-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU065861 from Sigma-Aldrich
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MISSION® esiRNA - EHU006771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14861 from Sigma-Aldrich
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MYO5A siRNA (Human) - CRH3068 from Cohesion Biosciences
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shRNA set against Human MYO5A (NM_000259.3) - SHH348260 from Creative biogene
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Human MYO5A siRNA - orb263570 from Biorbyt
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MYO5A shRNA Plasmid (Human) - CHH3068 from Cohesion Biosciences
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