| Gene Symbol |
PPOX
|
| Entrez Gene |
5498
|
| Alt Symbol |
PPO, V290M, VP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protoporphyrinogen oxidase
|
| Other Description |
-
|
| Swissprots |
Q5VTW8 D3DVG0 P50336
|
| Accessions |
AAC95467 AAG43994 AAG43995 AAK50375 AAK50376 AAK69607 AAK69608 AAK69609 EAW52635 EAW52636 EAW52637 EAW52638 EAW52639 EAW52640 EAW52641 P50336 AI357309 AK094855 BAG52942 AK298912 BAG61019 AK302298 BAG63638 AU076582 BC002357 AAH02357 BX384814 D38537 BAA07538 DC329287 DQ892215 ABM83141 DQ895411 ABM86337 U26446 AAA67690 XM_005245291 XP_005245348 XM_005245295 XP_005245352 XM_006711402 XP_006711465 XM_006711403 XP_006711466 XM_006711404 XP_006711467 XM_006711406 XP_006711469 XM_011509663 XP_011507965 XM_011509664 XP_011507966 XM_011509665 XP_011507967 XM_011509666 XP_011507968 XM_011509667 XP_011507969 XM_011509668 XP_011507970 XM_011509669 XP_011507971 XM_011509670 XP_011507972 XM_011509671 XP_011507973 XM_011509672 XP_011507974 XM_011509673 XP_011507975 XM_011509674 XP_011507976 XM_011509675 XP_011507977 XM_011509676 XP_011507978 XM_011509677 XP_011507979 XM_011509678 XP_011507980 XM_011509679 XP_011507981 XM_011509680 XP_011507982 XM_011509681 XP_011507983 XM_011509682 XP_011507984 XR_921850 NM_000309 NP_000300 NM_001122764 NP_001116236
|
| Function |
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. {ECO:0000269|PubMed:21048046, ECO:0000269|PubMed:23467411, ECO:0000269|PubMed:7713909}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
|
| Tissue Specificity |
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
|
| Top Pathways |
Porphyrin and chlorophyll metabolism
|