| Gene Symbol |
NLRC5
|
| Entrez Gene |
84166
|
| Alt Symbol |
CLR16.1, NOD27, NOD4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NLR family, CARD domain containing 5
|
| Other Description |
NOD-like receptor C5|caterpiller protein 16.1|nucleotide-binding oligomerization domain protein 4|nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5|nucleotide-binding oligomerization domains 27|protein NLRC5
|
| Swissprots |
Q86WI3 Q86VM7 Q8TEJ1 Q8TEE2 Q6P4A6 Q8NF42 Q969L7 B5MEF1 C9JMD8
|
| Accessions |
CAZ39543 EAW82898 EAW82899 EAW82900 EAW82901 EAW82902 Q86WI3 AA722775 AF389420 AAO59377 AK025212 AK025362 BAB15120 AK027414 BAB55096 AK027416 BAB55098 AK074133 BAB84959 AK074182 BAB85008 AK090439 BAC03420 AK097030 AL704292 BC040278 BC050527 AAH50527 BC063566 AAH63566 BC156512 AAI56513 BC172510 AAI72510 BI061907 BM463398 BM993764 BX640842 CAE45914 DB293035 EF452236 ABO40479 XM_005256193 XP_005256250 XM_005256194 XP_005256251 XM_005256195 XP_005256252 XM_005256196 XP_005256253 XM_005256197 XP_005256254 XM_005256199 XP_005256256 XM_005256201 XP_005256258 XM_006721297 XP_006721360 XM_006721298 XP_006721361 XM_006721300 XP_006721363 XM_011523373 XP_011521675 XM_011523374 XP_011521676 XM_011523375 XP_011521677 XM_011523376 XP_011521678 XR_429733 XR_429734 XR_933458 NM_032206 NP_115582
|
| Function |
Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. {ECO:0000269|PubMed:20061403, ECO:0000269|PubMed:20434986}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:20061403, ECO:0000269|PubMed:20434986}.
|
| Tissue Specificity |
Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate. {ECO:0000269|PubMed:20061403, ECO:0000269|PubMed:20434986}.
|