| Gene Symbol |
HMG20A
|
| Entrez Gene |
10363
|
| Alt Symbol |
HMGX1, HMGXB1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
high mobility group 20A
|
| Other Description |
HMG box domain containing 1|HMG box-containing protein 20A|HMG domain-containing protein 1|HMG domain-containing protein HMGX1|high mobility group protein 20A
|
| Swissprots |
D3DW78 A6NHY3 Q9NSF6 Q53G31 Q9NP66
|
| Accessions |
CAE89565 EAW99201 EAW99202 EAW99203 Q9NP66 AA233289 AB073664 AF146222 AAF66706 AK001601 BAA91782 AK025664 AK096546 AK223100 BAD96820 AK297449 BAG59873 AK311376 AK316281 BAH14652 AL355733 AL355737 CAB90816 AL355739 AL832087 BC021959 AAH21959 BT006716 AAP35362 DA333471 DB068283 DB213761 XM_011521158 XP_011519460 NM_001304504 NP_001291433 NM_001304505 NP_001291434 NM_018200 NP_060670
|
| Function |
Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:10773667}.
|
![Western Blot: HMG20A Overexpression Lysate (Adult Normal) [NBL1-11606] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HMG20A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8830_HMG20A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11606-img0002.jpg)