Gene Symbol |
Ptprf
|
Entrez Gene |
19268
|
Alt Symbol |
AA591035, LAR, LARS, RPTP-LAR
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
protein tyrosine phosphatase, receptor type, F
|
Other Description |
leukocyte antigen-related (LAR) PTP receptor|leukocyte common antigen related|receptor-type tyrosine-protein phosphatase F
|
Swissprots |
A2A8L5 Q6PG86 Q9EQ17
|
Accessions |
A2A8L5 EDL30516 EDL30517 AF300943 AAG40194 AI385919 AK133085 BAE21505 AK135889 AK161629 BAE36501 BC039767 BC052322 BC057166 AAH57166 BU055092 BU056582 CA315396 CD352108 CK634962 CV556730 CX201972 Z23049 CAA80584 Z23061 CAA80596 Z37988 CAA86070 XM_006502864 XP_006502927 XM_006502865 XP_006502928 XM_006502866 XP_006502929 XM_006502867 XP_006502930 XM_006502868 XP_006502931 XM_006502869 XP_006502932 XM_006502870 XP_006502933 XM_006502871 XP_006502934 XM_006502872 XP_006502935 XM_006502874 XP_006502937 XM_006502875 XP_006502938 XM_006502876 XP_006502939 NM_011213 NP_035343
|
Function |
Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity). {ECO:0000250}.
|
Subcellular Location |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
Tissue Specificity |
Expressed in the cell of the T lineage but not in cells of any other hemopoietic lineage. {ECO:0000269|PubMed:11241288}.
|
Top Pathways |
Adherens junction, Cell adhesion molecules (CAMs), Insulin signaling pathway
|