Gene Symbol | PRRX2 |
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Entrez Gene | 51450 |
Alt Symbol | PMX2, PRX2 |
Species | Human |
Gene Type | protein-coding |
Description | paired related homeobox 2 |
Other Description | PRX-2|paired mesoderm homeobox protein 2|paired-like homeodomain protein PRX2|paired-related homeobox protein 2 |
Swissprots | Q9UIB3 Q99811 Q5SZB5 |
Accessions | EAW87901 Q99811 AF061970 AAF17708 BC014645 AAH14645 U81600 AAB39864 XM_011518771 XP_011517073 XM_011518772 XP_011517074 NM_016307 NP_057391 |
Function | May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development. {ECO:0000269|PubMed:9665387}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}. |
Tissue Specificity | In fetal skin, highest expression found in cells of mesodermal origin within the dermal papilla of the developing hair shaft. Not detected in epidermis or dermis. In adult skin, weakly expressed within the basal layers of the epidermis. Not expressed in dermis. {ECO:0000269|PubMed:9665387}. |
PRX2 CRISPR/Cas9 KO Plasmid (h) - sc-405651 from Santa Cruz Biotechnology
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PRX2 HDR Plasmid (h) - sc-405651-HDR from Santa Cruz Biotechnology
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PRX2 Double Nickase Plasmid (h) - sc-405651-NIC from Santa Cruz Biotechnology
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PRX2 Double Nickase Plasmid (h2) - sc-405651-NIC-2 from Santa Cruz Biotechnology
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PRX2 CRISPR Activation Plasmid (h) - sc-405651-ACT from Santa Cruz Biotechnology
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PRX2 CRISPR Activation Plasmid (h2) - sc-405651-ACT-2 from Santa Cruz Biotechnology
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PRX2 Lentiviral Activation Particles (h) - sc-405651-LAC from Santa Cruz Biotechnology
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PRX2 Lentiviral Activation Particles (h2) - sc-405651-LAC-2 from Santa Cruz Biotechnology
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PRRX2 RNAi - H00051450-R01 from Novus Biologicals
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MISSION® esiRNA - EHU029331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17528 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17528 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02550 from Sigma-Aldrich
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PRRX2 siRNA (Human) - CRH9771 from Cohesion Biosciences
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shRNA set against Human PRRX2 (NM_016307.3) - SHH384296 from Creative biogene
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Human PRRX2 siRNA - orb270273 from Biorbyt
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PRRX2 shRNA Plasmid (Human) - CHH9771 from Cohesion Biosciences
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PRRX2 miRNA 3'UTR clone - MiUTR1H-08336 from Creative biogene
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