Gene Symbol | SPICE1 |
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Entrez Gene | 152185 |
Alt Symbol | CCDC52, SPICE |
Species | Human |
Gene Type | protein-coding |
Description | spindle and centriole associated protein 1 |
Other Description | coiled-coil domain containing 52|coiled-coil domain-containing protein 52|spindle and centriole protein|spindle and centriole-associated protein 1 |
Swissprots | Q8N0Z3 Q8WUX6 D3DN72 |
Accessions | EAW79634 EAW79635 EAW79636 EAW79637 Q8N0Z3 AK057966 AK126897 BAG54389 AK129575 AK296160 BAG58899 AL832148 CAD91167 AL832327 AY099107 AAM34495 BC019232 AAH19232 BC036951 AAH36951 BC038595 BP278430 U79249 XM_011512461 XP_011510763 NM_144718 NP_653319 |
Function | Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis. {ECO:0000269|PubMed:20736305}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:20736305}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:20736305}. |
CCDC52 CRISPR/Cas9 KO Plasmid (h) - sc-410341 from Santa Cruz Biotechnology
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CCDC52 HDR Plasmid (h) - sc-410341-HDR from Santa Cruz Biotechnology
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CCDC52 Double Nickase Plasmid (h) - sc-410341-NIC from Santa Cruz Biotechnology
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CCDC52 Double Nickase Plasmid (h2) - sc-410341-NIC-2 from Santa Cruz Biotechnology
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CCDC52 CRISPR Activation Plasmid (h) - sc-410341-ACT from Santa Cruz Biotechnology
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CCDC52 CRISPR Activation Plasmid (h2) - sc-410341-ACT-2 from Santa Cruz Biotechnology
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CCDC52 Lentiviral Activation Particles (h) - sc-410341-LAC from Santa Cruz Biotechnology
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CCDC52 Lentiviral Activation Particles (h2) - sc-410341-LAC-2 from Santa Cruz Biotechnology
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CCDC52 siRNA (h) - sc-78503 from Santa Cruz Biotechnology
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CCDC52 shRNA Plasmid (h) - sc-78503-SH from Santa Cruz Biotechnology
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CCDC52 shRNA (h) Lentiviral Particles - sc-78503-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU031071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20472 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20472 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11625 from Sigma-Aldrich
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SPICE1 siRNA (Human) - CRJ5733 from Cohesion Biosciences
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SPICE1 - MBS8207092 from MyBioSource
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shRNA set against Human SPICE1 (NM_144718.3) - SHH416672 from Creative biogene
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Human SPICE1 siRNA - orb276234 from Biorbyt
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SPICE1 shRNA Plasmid (Human) - CHJ5733 from Cohesion Biosciences
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SPICE1 miRNA 3'UTR clone - MiUTR4H-TG10808 from Creative biogene
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