Gene Symbol | PPAPDC1A |
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Entrez Gene | 196051 |
Alt Symbol | DPPL2, PPAPDC1 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidic acid phosphatase type 2 domain containing 1A |
Other Description | diacylglycerol pyrophosphate like 2|phosphatidate phosphatase PPAPDC1A|phosphatidic acid phosphatase type 2 domain-containing protein 1A |
Swissprots | Q5VZY1 Q0IIP2 Q08EQ2 Q5VZY2 A2RU82 Q495B4 |
Accessions | EAW49368 EAW49369 Q5VZY2 AK098668 AK296273 BAH12299 AK310178 BC101267 AAI01268 BC101268 AAI01269 BC101269 AAI01270 BC122535 AAI22536 BC132787 AAI32788 BI550027 CR739184 DR000933 HQ258170 ADR82924 XM_005269592 XP_005269649 XM_006717685 XP_006717748 XM_006717686 XP_006717749 XM_006717688 XP_006717751 XM_011539444 XP_011537746 XM_011539445 XP_011537747 XM_011539446 XP_011537748 XM_011539447 XP_011537749 XM_011539448 XP_011537750 NM_001030059 NP_001025230 |
Function | Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. {ECO:0000269|PubMed:17590538}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed mainly to the brain, kidney and testis, and to a lesser extent the bone marrow, thymus, prostate, liver and uterus. {ECO:0000269|PubMed:17590538}. |
DPPL2 CRISPR/Cas9 KO Plasmid (h) - sc-414952 from Santa Cruz Biotechnology
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DPPL2 HDR Plasmid (h) - sc-414952-HDR from Santa Cruz Biotechnology
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DPPL2 Double Nickase Plasmid (h) - sc-414952-NIC from Santa Cruz Biotechnology
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DPPL2 Double Nickase Plasmid (h2) - sc-414952-NIC-2 from Santa Cruz Biotechnology
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DPPL2 CRISPR Activation Plasmid (h) - sc-414952-ACT from Santa Cruz Biotechnology
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DPPL2 CRISPR Activation Plasmid (h2) - sc-414952-ACT-2 from Santa Cruz Biotechnology
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DPPL2 Lentiviral Activation Particles (h) - sc-414952-LAC from Santa Cruz Biotechnology
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DPPL2 Lentiviral Activation Particles (h2) - sc-414952-LAC-2 from Santa Cruz Biotechnology
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DPPL2 siRNA (h) - sc-90809 from Santa Cruz Biotechnology
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DPPL2 shRNA Plasmid (h) - sc-90809-SH from Santa Cruz Biotechnology
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DPPL2 shRNA (h) Lentiviral Particles - sc-90809-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU103031 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0446 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0447 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0445 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17199 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17199 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02719 from Sigma-Aldrich
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PPAPDC1A siRNA (Human) - CRJ6163 from Cohesion Biosciences
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Human PPAPDC1A siRNA - orb276664 from Biorbyt
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PPAPDC1A shRNA Plasmid (Human) - CHJ6163 from Cohesion Biosciences
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