Gene Symbol |
FABP5
|
Entrez Gene |
2171
|
Alt Symbol |
E-FABP, EFABP, KFABP, PA-FABP, PAFABP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
fatty acid binding protein 5 (psoriasis-associated)
|
Other Description |
epidermal-type fatty acid-binding protein|fatty acid-binding protein, epidermal|psoriasis-associated fatty acid-binding protein homolog
|
Swissprots |
B2R4K0 Q01469
|
Accessions |
ADU05470 EAW87088 Q01469 AK226036 AK311856 BAG34797 BC019385 AAH19385 BC070303 AAH70303 BT007449 AAP36117 CN278427 DQ891285 ABM82211 DQ894470 ABM85396 M94856 AAA58467 NM_001444 NP_001435
|
Function |
High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
|
Subcellular Location |
Cytoplasm.
|
Tissue Specificity |
Keratinocytes; highly expressed in psoriatic skin.
|
Top Pathways |
PPAR signaling pathway
|