SCARB1

Gene Symbol	SCARB1
Entrez Gene	949
Alt Symbol	CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1
Species	Human
Gene Type	protein-coding
Description	scavenger receptor class B, member 1
Other Description	CD36 and LIMPII analogous 1|CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1|scavenger receptor class B member 1|scavenger receptor class B type III
Swissprots	Q14016 F8W8N0 Q52LZ5 Q8WTV0 Q6KFX4
Accessions	EAW98458 EAW98459 EAW98460 EAW98461 EAW98462 Q8WTV0 AB209436 BAD92673 AF254409 AAF91347 AF515445 AAQ08185 AK124112 BAG54008 AK302779 BAG63983 AK304730 BAG65493 BC022087 BC034322 BC080647 AAH80647 BC093732 AAH93732 BC112037 AAI12038 BC143319 AAI43320 BG770204 CA428516 DQ892837 ABM83763 DQ896083 ABM87082 Z22555 CAA80277 NM_001082959 NP_001076428 NM_005505 NP_005496
Function	Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein. Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.
Tissue Specificity	Widely expressed.
Top Pathways	Phagosome, Hepatitis C, Bile secretion, Fat digestion and absorption, Vitamin digestion and absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Scavenging Receptor SR-BI protein fragment - ab182680 from Abcam Category Protein Prices $449.00 Sizes 50 µg Source HEK 293 cells Species Human

Human Scavenging Receptor SR-BI full length protein - ab158057 from Abcam Category Protein Source Wheat germ Species Human

Mouse Scavenging Receptor SR-BI peptide - ab28536 from Abcam Category Peptide

SCARB1 / SR-BI Antibody Blocking Peptide - LS-E6751 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SCARB1 / SR-BI Antibody Blocking Peptide - LS-E23047 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SCARB1 / SR-BI Antibody Blocking Peptide - LS-E30711 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SR-BI Blocking Peptide - NB400-131PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg

SR-BI Blocking Peptide - NB400-101PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg

Recombinant Human SR-BI Protein - H00000949-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SCARB1-AntibodyN-term-Blocking-peptide - BP19624a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human SCARB1 His tag protein - orb83294 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 10 μg, 20 μg Source Human Species Human

Human SCARB1 Fc His tag protein - orb83293 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Human Species Human

Human SCARB1 protein - orb246607 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

SCARB1 - H00000949-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

SCARB1 Control Peptide - AP30764CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SCARB1 Peptide - 5193P from ProSci Category Peptide Species Human

SCARB1 Recombinant Protein - 96-673 from ProSci Category Protein Prices $450.00 Sizes 50 µg Source HEK293 cells Species Human

SCARB1 fusion protein - ag15759 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SCARB1 fusion protein - ag15974 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human SCARB1, Fc-His tagged - SCARB1-846H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human SCARB1, His tagged - SCARB1-848H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human Scavenger Receptor Class B, Member 1, Fc-His - SCARB1-852H from Creative Biomart Category Protein Source Human

Recombinant Human SCARB1 - SCARB1-509H from Creative Biomart Category Protein Source HEK293 cells Species Human

Human Scavenger Receptor Class B Type I Recombinant, Fc - RKQ8WTV0 from Reprokine Category Protein Prices $160.00, $550.00, $1,950.00 Sizes 10 µg, 50 µg, 200 µg Source Optimized DNA sequence encoding I extracellular domain of Human Scavenger Receptor Class B Type I (SR-BI) (PRO33-TYR443) including a IgG1 C-terminal tag was expressed in HEK293 cells. Species Human

Recombinant Scavenger Receptor Class B Member 1 (SCARB1) - RPH194Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

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