Gene Symbol | ADCY8 |
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Entrez Gene | 114 |
Alt Symbol | AC8, ADCY3, HBAC1 |
Species | Human |
Gene Type | protein-coding |
Description | adenylate cyclase 8 (brain) |
Other Description | ATP pyrophosphate-lyase 8|adenylate cyclase type 8|adenylate cyclase type VIII|adenylyl cyclase 8|adenylyl cyclase-8, brain|ca(2+)/calmodulin-activated adenylyl cyclase |
Swissprots | P40145 |
Accessions | CCQ43094 EAW92135 P40145 BC111456 AAI11457 DQ104739 AAZ13596 DR003657 M83533 AAA35523 Z35309 CAA84552 XM_005250769 XP_005250826 XM_006716501 XP_006716564 NM_001115 NP_001106 |
Function | This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Top Pathways | Gap junction, Progesterone-mediated oocyte maturation, Long-term potentiation, Adrenergic signaling in cardiomyocytes, Rap1 signaling pathway |
A cyclase VIII CRISPR/Cas9 KO Plasmid (h) - sc-402004 from Santa Cruz Biotechnology
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A cyclase VIII HDR Plasmid (h) - sc-402004-HDR from Santa Cruz Biotechnology
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A cyclase VIII Double Nickase Plasmid (h) - sc-402004-NIC from Santa Cruz Biotechnology
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A cyclase VIII Double Nickase Plasmid (h2) - sc-402004-NIC-2 from Santa Cruz Biotechnology
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A cyclase VIII CRISPR Activation Plasmid (h) - sc-402004-ACT from Santa Cruz Biotechnology
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A cyclase VIII CRISPR Activation Plasmid (h2) - sc-402004-ACT-2 from Santa Cruz Biotechnology
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A cyclase VIII Lentiviral Activation Particles (h) - sc-402004-LAC from Santa Cruz Biotechnology
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A cyclase VIII Lentiviral Activation Particles (h2) - sc-402004-LAC-2 from Santa Cruz Biotechnology
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A cyclase VIII siRNA (h) - sc-40325 from Santa Cruz Biotechnology
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A cyclase VIII shRNA Plasmid (h) - sc-40325-SH from Santa Cruz Biotechnology
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A cyclase VIII shRNA (h) Lentiviral Particles - sc-40325-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU040381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2867 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2867 from Sigma-Aldrich
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ADCY8 siRNA (Human) - CRH0076 from Cohesion Biosciences
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Adenylate Cyclase 8 RNAi - H00000114-R01 from Novus Biologicals
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ADCY8 - MBS8220509 from MyBioSource
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shRNA set against Human ADCY8(NM_001115.2) - SHG041527 from Creative biogene
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ADCY8 shRNA Plasmid (Human) - CHH0076 from Cohesion Biosciences
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ADCY8 miRNA 3'UTR clone - MiUTR1H-00189 from Creative biogene
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