Gene Symbol | Calcrl |
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Entrez Gene | 25029 |
Alt Symbol | CLR, Crlr, RATCRLR, RNCLR |
Species | Rat |
Gene Type | protein-coding |
Description | calcitonin receptor-like |
Other Description | CGRP type 1 receptor|calcitonin gene-related peptide type 1 receptor|calcitonin receptor-like receptor |
Swissprots | Q63118 |
Accessions | EDL79299 EDL79300 Q63118 L27487 X70658 CAA49997 XM_006234438 XP_006234500 XM_006234439 XP_006234501 NM_012717 NP_036849 |
Function | Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Vascular smooth muscle contraction, Neuroactive ligand-receptor interaction |
CompoZr® Knockout ZFN Kit - CKOZFN51401 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND51401 from Sigma-Aldrich
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CALCRL siRNA (Rat) - CRR0400 from Cohesion Biosciences
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CALCRL - MBS8207132 from MyBioSource
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shRNA set against Rat Calcrl(NM_012717.1) - SHG137143 from Creative biogene
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Rat CALCRL siRNA - orb295249 from Biorbyt
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CALCRL shRNA Plasmid (Rat) - CHR0400 from Cohesion Biosciences
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CALCRL miRNA 3'UTR clone - MiUTR1R-00695 from Creative biogene
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