| Gene Symbol |
TFF3
|
| Entrez Gene |
7033
|
| Alt Symbol |
ITF, P1B, TFI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
trefoil factor 3 (intestinal)
|
| Other Description |
polypeptide P1.B|trefoil factor 3
|
| Swissprots |
Q07654 Q96NX0 E9PBB5 Q9UDA5
|
| Accessions |
AAA83628 BAA95531 BAB13731 EAX09571 EAX09572 Q07654 AF432265 AAL28111 BC017859 AAH17859 BQ016069 DQ891963 ABM82889 DQ895153 ABM86079 L08044 AAA36766 L15203 AAA59981 NM_003226 NP_003217
|
| Function |
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). {ECO:0000269|PubMed:11694446}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:8454642}. Cytoplasm {ECO:0000269|PubMed:10824705, ECO:0000269|PubMed:8454642}.
|
| Tissue Specificity |
Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricular, periventricular and supraoptic nuclei (at protein level). {ECO:0000269|PubMed:8346203, ECO:0000269|PubMed:8454642}.
|