Gene Symbol | TOB2 |
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Entrez Gene | 10766 |
Alt Symbol | TOB4, TOBL, TROB2 |
Species | Human |
Gene Type | protein-coding |
Description | transducer of ERBB2, 2 |
Other Description | protein Tob2|protein Tob4|transducer of erbB-2 2 |
Swissprots | Q14106 Q6FHR7 Q9UBI0 Q9BY97 Q6PIT9 |
Accessions | Q14106 AB035207 BAA87042 AB051450 BAB33333 AI362988 AL133080 BC028919 AAH28919 BC038957 AAH38957 BM453650 CR456594 CAG30480 CR541684 CAG46485 CU013194 CAK54625 CU013482 CAK54924 D64109 BAA10971 XM_005261315 XP_005261372 XM_006724105 XP_006724168 NM_016272 NP_057356 |
Function | Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Ubiquitous. |
Top Pathways | RNA degradation |
TOB2 CRISPR/Cas9 KO Plasmid (h) - sc-404242 from Santa Cruz Biotechnology
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TOB2 HDR Plasmid (h) - sc-404242-HDR from Santa Cruz Biotechnology
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TOB2 Double Nickase Plasmid (h) - sc-404242-NIC from Santa Cruz Biotechnology
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TOB2 Double Nickase Plasmid (h2) - sc-404242-NIC-2 from Santa Cruz Biotechnology
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TOB2 CRISPR Activation Plasmid (h) - sc-404242-ACT from Santa Cruz Biotechnology
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TOB2 CRISPR Activation Plasmid (h2) - sc-404242-ACT-2 from Santa Cruz Biotechnology
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TOB2 Lentiviral Activation Particles (h) - sc-404242-LAC from Santa Cruz Biotechnology
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TOB2 Lentiviral Activation Particles (h2) - sc-404242-LAC-2 from Santa Cruz Biotechnology
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TOB2 siRNA (h) - sc-37506 from Santa Cruz Biotechnology
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TOB2 shRNA Plasmid (h) - sc-37506-SH from Santa Cruz Biotechnology
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TOB2 shRNA (h) Lentiviral Particles - sc-37506-V from Santa Cruz Biotechnology
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TOB2 RNAi - H00010766-R01 from Novus Biologicals
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MISSION® esiRNA - EHU108341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21806 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21806 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11833 from Sigma-Aldrich
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TOB2 siRNA (Human) - CRH7335 from Cohesion Biosciences
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TOB2 - MBS8236058 from MyBioSource
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shRNA set against Human TOB2 (NM_016272.3) - SHH432632 from Creative biogene
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shRNA set against Human TOB2(NM_016272.3) - SHL086844 from Creative biogene
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Human TOB2 siRNA - orb267837 from Biorbyt
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TOB2 shRNA Plasmid (Human) - CHH7335 from Cohesion Biosciences
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TOB2 miRNA 3'UTR clone - MiUTR1H-10635 from Creative biogene
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