Gene Symbol | GJA8 |
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Entrez Gene | 2703 |
Alt Symbol | CAE, CAE1, CTRCT1, CX50, CZP1, MP70 |
Species | Human |
Gene Type | protein-coding |
Description | gap junction protein, alpha 8, 50kDa |
Other Description | cell surface glycoprotein|connexin 50|connexin-50|gap junction alpha-8 protein|gap junction membrane channel protein alpha-8|gap junction protein alpha 8 50kDa|lens fiber protein MP70|lens intrinsic membrane protein MP70 |
Swissprots | Q9NP25 P48165 Q5VVN9 A7L5M5 |
Accessions | AAA77062 AAF32309 ABS11172 AIT70949 AIT70950 AIT70951 AIT70952 AIT70953 AIT70954 AIT70955 AIT70956 AIT70957 AIT70958 AIT70959 AIT70960 AIT70961 AIT70962 AIT70963 AIT70964 CAH72387 EAW50926 P48165 AI364417 BC140363 AAI40364 BC146507 AAI46508 BQ184886 CD674975 DB476698 KJ534845 AHW56485 XM_011509416 XP_011507718 XM_011509417 XP_011507719 NM_005267 NP_005258 |
Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
Tissue Specificity | Eye lens. |
connexin 50 CRISPR/Cas9 KO Plasmid (h) - sc-404332 from Santa Cruz Biotechnology
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connexin 50 HDR Plasmid (h) - sc-404332-HDR from Santa Cruz Biotechnology
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connexin 50 Double Nickase Plasmid (h) - sc-404332-NIC from Santa Cruz Biotechnology
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connexin 50 Double Nickase Plasmid (h2) - sc-404332-NIC-2 from Santa Cruz Biotechnology
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connexin 50 CRISPR Activation Plasmid (h) - sc-404332-ACT from Santa Cruz Biotechnology
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connexin 50 CRISPR Activation Plasmid (h2) - sc-404332-ACT-2 from Santa Cruz Biotechnology
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connexin 50 Lentiviral Activation Particles (h) - sc-404332-LAC from Santa Cruz Biotechnology
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connexin 50 Lentiviral Activation Particles (h2) - sc-404332-LAC-2 from Santa Cruz Biotechnology
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connexin 50 siRNA (h) - sc-43083 from Santa Cruz Biotechnology
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connexin 50 shRNA Plasmid (h) - sc-43083-SH from Santa Cruz Biotechnology
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connexin 50 shRNA (h) Lentiviral Particles - sc-43083-V from Santa Cruz Biotechnology
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Connexin 50/GJA8 RNAi - H00002703-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9306 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9306 from Sigma-Aldrich
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GJA8 siRNA (Human) - CRH1804 from Cohesion Biosciences
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GJA8 - MBS8216638 from MyBioSource
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shRNA set against Human Gja8 (NM_005267.4) - SHH301354 from Creative biogene
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Human GJA8 siRNA - orb262306 from Biorbyt
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GJA8 shRNA Plasmid (Human) - CHH1804 from Cohesion Biosciences
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GJA8 miRNA 3'UTR clone - MiUTR4H-TG03825 from Creative biogene
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