Gene Symbol | Pxn |
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Entrez Gene | 19303 |
Alt Symbol | AW108311, AW123232, Pax |
Species | Mouse |
Gene Type | protein-coding |
Description | paxillin |
Other Description | - |
Swissprots | Q8VI37 Q3TB62 Q3TZQ6 Q8VI36 |
Accessions | BAA32207 EDL19854 EDL19855 Q8VI36 AF293882 AAL71909 AF293883 AAL71910 AK084243 AK148060 BAE28319 AK149933 BAE29176 AK167299 BAE39404 AK171226 AK171436 BAE42452 AK180209 AK191714 AK194144 AK195488 AK197379 AK198032 AK198760 AK205143 AK206113 AK206605 AK208911 AK209978 AK211839 AK213554 AK214527 AK214775 AK215379 AK215544 AK218322 AK219507 AV025054 AW123232 BC003298 AAH03298 BC025493 BC152794 AAI52795 BY198095 XM_006530202 XP_006530265 XM_006530203 XP_006530266 XM_006530204 XP_006530267 XM_006530205 XP_006530268 XM_006530206 XP_006530269 XM_006530207 XP_006530270 NM_011223 NP_035353 NM_133915 NP_598676 |
Function | Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, focal adhesion {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000269|PubMed:8940124}. Note=Colocalizes with integrins at the cell periphery. |
Top Pathways | VEGF signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Chemokine signaling pathway, Bacterial invasion of epithelial cells |
paxillin CRISPR/Cas9 KO Plasmid (m) - sc-422546 from Santa Cruz Biotechnology
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paxillin HDR Plasmid (m) - sc-422546-HDR from Santa Cruz Biotechnology
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paxillin Double Nickase Plasmid (m) - sc-422546-NIC from Santa Cruz Biotechnology
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paxillin Double Nickase Plasmid (m2) - sc-422546-NIC-2 from Santa Cruz Biotechnology
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paxillin CRISPR Activation Plasmid (m) - sc-422546-ACT from Santa Cruz Biotechnology
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paxillin CRISPR Activation Plasmid (m2) - sc-422546-ACT-2 from Santa Cruz Biotechnology
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paxillin Lentiviral Activation Particles (m) - sc-422546-LAC from Santa Cruz Biotechnology
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paxillin Lentiviral Activation Particles (m2) - sc-422546-LAC-2 from Santa Cruz Biotechnology
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paxillin siRNA (m) - sc-36197 from Santa Cruz Biotechnology
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paxillin shRNA Plasmid (m) - sc-36197-SH from Santa Cruz Biotechnology
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paxillin shRNA (m) Lentiviral Particles - sc-36197-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN39700 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND39700 from Sigma-Aldrich
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PXN siRNA (Mouse) - CRM3355 from Cohesion Biosciences
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shRNA set against Mouse PXN (NM_011223.2) - SHH387348 from Creative biogene
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shRNA set against Mouse Pxn(NM_011223.2) - SHR155676 from Creative biogene
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shRNA set against Mouse Pxn(NM_133915.2) - SHR155730 from Creative biogene
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Mouse PXN siRNA - orb282831 from Biorbyt
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PXN shRNA Plasmid (Mouse) - CHM3355 from Cohesion Biosciences
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PXN miRNA 3'UTR clone - MiUTR1M-09800 from Creative biogene
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PXN miRNA 3'UTR clone - MiUTR1M-09801 from Creative biogene
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