Gene Symbol | St3gal5 |
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Entrez Gene | 20454 |
Alt Symbol | 3S-T, Siat9, [a]2 |
Species | Mouse |
Gene Type | protein-coding |
Description | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
Other Description | CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase|GM3 synthase|GM3-specific sialytransferase|ST3GalV|ganglioside GM3 synthase|lactosylceramide alpha-2,3-sialyltransferase|mST3Gal V|sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase) |
Swissprots | Q9CZ65 Q9QWF8 Q9QWF9 O88829 Q91YF3 Q3TMT6 Q3TY01 B2RRS1 Q91YF2 |
Accessions | CAC79652 CAC79653 CAC79654 CAC79655 EDK98959 EDK98960 O88829 AB013302 BAA76467 AB018048 BAA33491 AF119416 AAF66147 AK012961 BAB28571 AK158594 AK159000 BAE34763 AK165726 BAE38355 AK196129 AK208200 AK209139 AK216504 AK217364 AK217808 AV307729 AW488475 BB866983 BC138557 AAI38558 BC138559 AAI38560 BY160366 Y15003 CAA75235 XM_006505816 XP_006505879 XM_006505817 XP_006505880 XM_006505818 XP_006505881 XM_006505819 XP_006505882 XM_006505820 XP_006505883 XM_011241266 XP_011239568 XM_011241267 XP_011239569 NM_001035228 NP_001030305 NM_011375 NP_035505 |
Function | Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D- glucosylceramide). {ECO:0000269|PubMed:12629211}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Top Pathways | Glycosphingolipid biosynthesis - ganglio series |
GM3 Synthase CRISPR/Cas9 KO Plasmid (m) - sc-422946 from Santa Cruz Biotechnology
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GM3 Synthase HDR Plasmid (m) - sc-422946-HDR from Santa Cruz Biotechnology
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GM3 Synthase Double Nickase Plasmid (m) - sc-422946-NIC from Santa Cruz Biotechnology
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GM3 Synthase Double Nickase Plasmid (m2) - sc-422946-NIC-2 from Santa Cruz Biotechnology
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GM3 Synthase CRISPR Activation Plasmid (m) - sc-422946-ACT from Santa Cruz Biotechnology
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GM3 Synthase CRISPR Activation Plasmid (m2) - sc-422946-ACT-2 from Santa Cruz Biotechnology
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GM3 Synthase Lentiviral Activation Particles (m) - sc-422946-LAC from Santa Cruz Biotechnology
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GM3 Synthase Lentiviral Activation Particles (m2) - sc-422946-LAC-2 from Santa Cruz Biotechnology
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GM3 Synthase siRNA (m) - sc-72298 from Santa Cruz Biotechnology
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GM3 Synthase shRNA Plasmid (m) - sc-72298-SH from Santa Cruz Biotechnology
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GM3 Synthase shRNA (m) Lentiviral Particles - sc-72298-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU081991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN42120 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42120 from Sigma-Aldrich
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ST3GAL5 siRNA (Mouse) - CRM3728 from Cohesion Biosciences
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ST3GAL5 - MBS8239882 from MyBioSource
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shRNA set against Mouse ST3GAL5 (NM_011375.2) - SHH418852 from Creative biogene
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shRNA set against Mouse St3gal5(NM_011375.2) - SHL038178 from Creative biogene
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shRNA set against Mouse St3gal5(NM_001035228.1) - SHL038262 from Creative biogene
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ST3GAL5 shRNA Plasmid (Mouse) - CHM3728 from Cohesion Biosciences
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ST3GAL5 miRNA 3'UTR clone - MiUTR1M-11274 from Creative biogene
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