Gene Symbol | LPIN3 |
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Entrez Gene | 64900 |
Alt Symbol | LIPN3L, SMP2 |
Species | Human |
Gene Type | protein-coding |
Description | lipin 3 |
Other Description | lipin-3|phosphatidate phosphatase LPIN3 |
Swissprots | Q9BQK8 Q9UJE5 B2RTT5 Q9NPY8 Q5TDB9 |
Accessions | EAW75985 EAW75986 Q9BQK8 BC140806 AAI40807 BC144598 BX505800 BX647082 BX648609 XM_005260516 XP_005260573 XM_006723863 XP_006723926 XM_011528996 XP_011527298 XM_011528997 XP_011527299 XM_011528998 XP_011527300 XM_011528999 XP_011527301 XM_011529000 XP_011527302 XM_011529001 XP_011527303 XM_011529002 XP_011527304 XM_011529003 XP_011527305 XM_011529004 XP_011527306 XM_011529005 XP_011527307 XM_011529006 XP_011527308 XR_430311 XR_936609 XR_936610 NM_022896 NM_001301860 NP_001288789 NR_126051 |
Function | Regulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Significant expression in intestine and other regions of the gastrointestinal tract. {ECO:0000269|PubMed:17158099}. |
Top Pathways | Glycerolipid metabolism, Glycerophospholipid metabolism |
Lipin-3 CRISPR/Cas9 KO Plasmid (h) - sc-410107 from Santa Cruz Biotechnology
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Lipin-3 HDR Plasmid (h) - sc-410107-HDR from Santa Cruz Biotechnology
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Lipin-3 Double Nickase Plasmid (h) - sc-410107-NIC from Santa Cruz Biotechnology
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Lipin-3 Double Nickase Plasmid (h2) - sc-410107-NIC-2 from Santa Cruz Biotechnology
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Lipin-3 CRISPR Activation Plasmid (h) - sc-410107-ACT from Santa Cruz Biotechnology
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Lipin-3 CRISPR Activation Plasmid (h2) - sc-410107-ACT-2 from Santa Cruz Biotechnology
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Lipin-3 Lentiviral Activation Particles (h) - sc-410107-LAC from Santa Cruz Biotechnology
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Lipin-3 Lentiviral Activation Particles (h2) - sc-410107-LAC-2 from Santa Cruz Biotechnology
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Lipin-3 siRNA (h) - sc-60944 from Santa Cruz Biotechnology
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Lipin-3 shRNA Plasmid (h) - sc-60944-SH from Santa Cruz Biotechnology
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Lipin-3 shRNA (h) Lentiviral Particles - sc-60944-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU143491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12657 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12657 from Sigma-Aldrich
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LPIN3 siRNA (Human) - CRJ2134 from Cohesion Biosciences
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shRNA set against Human Lpin3 (NM_022896.1) - SHH333595 from Creative biogene
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LPIN3 shRNA Plasmid (Human) - CHJ2134 from Cohesion Biosciences
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LPIN3 miRNA 3'UTR clone - MiUTR1H-05884 from Creative biogene
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