Gene Symbol | CDC25B |
---|---|
Entrez Gene | 994 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cell division cycle 25B |
Other Description | M-phase inducer phosphatase 2|dual specificity phosphatase Cdc25B |
Swissprots | Q5JX77 O43551 D3DVY1 P30305 D3DVY2 Q13971 D3DVY4 Q6RSS1 D3DVY3 Q9BRA6 |
Accessions | AAB94622 AAB94623 AAB94624 AAB94625 AAR26469 CAA65303 EAX10491 EAX10493 EAX10494 EAX10496 EAX10498 EAX10499 EAX10500 EAX10501 P30305 AK092713 BAG52600 AK124284 AK295573 BAG58472 AK299028 BAG61105 AK299192 BAG61235 AL561439 BC006395 AAH06395 BC009953 AAH09953 BC051711 AAH51711 BM793120 BX640836 CAE45909 BX647988 DA065196 DA107932 DB477384 FR695900 CBX26628 FR695901 CBX26629 M81934 AAA58416 S78187 AAB21139 Z68092 CAA92108 XR_937181 NM_001287516 NP_001274445 NM_001287517 NP_001274446 NM_001287518 NP_001274447 NM_001287519 NP_001274448 NM_001287520 NP_001274449 NM_001287522 NP_001274451 NM_001287524 NP_001274453 NM_004358 NP_004349 NM_021872 NP_068658 NM_021873 NP_068659 NM_021874 NM_212530 |
Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. {ECO:0000269|PubMed:17332740}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. |
Top Pathways | Cell cycle, Progesterone-mediated oocyte maturation, MAPK signaling pathway, MicroRNAs in cancer |
Mouse/Human/Rat Phospho-CDC25B (Ser323) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1080 from LifeSpan Bioscience
|
||||||||||
Human Phospho-CDC25B (Ser353) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1335 from LifeSpan Bioscience
|
||||||||||
M-phase inducer phosphatase 2 (CDC25B), Human, ELISA Kit - CSB-EL004995HU from ARP American Research Products
|
||||||||||
cell division cycle 25 homolog B (S. pombe) , ELISA Kit - MBS931754 from MyBioSource
|
||||||||||
CDC25B (Phospho-Ser323) Colorimetric Cell-Based ELISA Kit - CBP1056 from Assay Biotechnology
|
||||||||||
CDC25B (Phospho-Ser353) Colorimetric Cell-Based ELISA Kit - CBP1343 from Assay Biotechnology
|
||||||||||
Human M-phase inducer phosphatase 2(CDC25B) ELISA kit - CSB-EL004995HU from Cusabio
|
||||||||||
CDC25B (Phospho-Ser323) ELISA Kit - DEIA-XYA377 from Creative Diagnostics
|
||||||||||
CDC25B (Phospho-Ser353) ELISA Kit - DEIA-XYA378 from Creative Diagnostics
|
||||||||||
Human M-phase inducer phosphatase 2 (CDC25B) ELISA Kit - EKC34650 from Biomatik
|
||||||||||
Custom Human CDC25B ELISA - ELH-CDC25B-1 from RayBiotech
|
||||||||||
Human CDC25B ELISA Kit - E007675 from Biobool
|
||||||||||
CDC25B ELISA Kit (Human) (OKCA01365) - OKCA01365 from Aviva Systems Biology
|
||||||||||
Custom Human CDC25B ELISA Kit - orb384508 from Biorbyt
|