| Gene Symbol | UGT2B7 |
|---|---|
| Entrez Gene | 7364 |
| Alt Symbol | UDPGT 2B9, UDPGT2B7, UDPGTH2, UGT2B9 |
| Species | Human |
| Gene Type | protein-coding |
| Description | UDP glucuronosyltransferase 2 family, polypeptide B7 |
| Other Description | 3,4-catechol estrogen specific|3,4-catechol estrogen-specific UDPGT|UDP glucuronosyltransferase 2B7|UDP-glucuronosyltransferase 2B7|UDP-glucuronosyltransferase 2B9|UDP-glucuronyltransferase, family 2, beta-7|UDPGT 2B7|UDPGTh-2 |
| Swissprots | P16662 B2R810 Q6GTW0 |
| Accessions | AAG01472 AAO65542 AAY41045 EAX05582 EAX05583 EAX05584 EAX05585 P16662 AK223142 BAD96862 AK313190 BAG36007 AW614236 BC030974 AAH30974 DQ893657 ABM84583 DQ895814 ABM86740 J05428 AAA36793 S82485 AAD14400 XM_005265702 XP_005265759 XM_011532229 XP_011530531 XM_011532230 XP_011530532 XM_011532231 XP_011530533 NM_001074 NP_001065 |
| Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. {ECO:0000269|PubMed:17442341}. |
| Subcellular Location | Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450 |