Gene Symbol | UGT2B7 |
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Entrez Gene | 7364 |
Alt Symbol | UDPGT 2B9, UDPGT2B7, UDPGTH2, UGT2B9 |
Species | Human |
Gene Type | protein-coding |
Description | UDP glucuronosyltransferase 2 family, polypeptide B7 |
Other Description | 3,4-catechol estrogen specific|3,4-catechol estrogen-specific UDPGT|UDP glucuronosyltransferase 2B7|UDP-glucuronosyltransferase 2B7|UDP-glucuronosyltransferase 2B9|UDP-glucuronyltransferase, family 2, beta-7|UDPGT 2B7|UDPGTh-2 |
Swissprots | P16662 B2R810 Q6GTW0 |
Accessions | AAG01472 AAO65542 AAY41045 EAX05582 EAX05583 EAX05584 EAX05585 P16662 AK223142 BAD96862 AK313190 BAG36007 AW614236 BC030974 AAH30974 DQ893657 ABM84583 DQ895814 ABM86740 J05428 AAA36793 S82485 AAD14400 XM_005265702 XP_005265759 XM_011532229 XP_011530531 XM_011532230 XP_011530532 XM_011532231 XP_011530533 NM_001074 NP_001065 |
Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. {ECO:0000269|PubMed:17442341}. |
Subcellular Location | Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450 |
UGT2B7 CRISPR/Cas9 KO Plasmid (h) - sc-404209 from Santa Cruz Biotechnology
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UGT2B7 HDR Plasmid (h) - sc-404209-HDR from Santa Cruz Biotechnology
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UGT2B7 Double Nickase Plasmid (h) - sc-404209-NIC from Santa Cruz Biotechnology
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UGT2B7 Double Nickase Plasmid (h2) - sc-404209-NIC-2 from Santa Cruz Biotechnology
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UGT2B7 CRISPR Activation Plasmid (h) - sc-404209-ACT from Santa Cruz Biotechnology
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UGT2B7 CRISPR Activation Plasmid (h2) - sc-404209-ACT-2 from Santa Cruz Biotechnology
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UGT2B7 Lentiviral Activation Particles (h) - sc-404209-LAC from Santa Cruz Biotechnology
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UGT2B7 Lentiviral Activation Particles (h2) - sc-404209-LAC-2 from Santa Cruz Biotechnology
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UGT2B7 siRNA (h) - sc-106670 from Santa Cruz Biotechnology
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UGT2B7 shRNA Plasmid (h) - sc-106670-SH from Santa Cruz Biotechnology
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UGT2B7 shRNA (h) Lentiviral Particles - sc-106670-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22473 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22473 from Sigma-Aldrich
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UGT2B7 siRNA (Human) - CRH5035 from Cohesion Biosciences
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UGT2B7 - MBS829618 from MyBioSource
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shRNA set against Human Ugt2b (NM_001074.2) - SHH440168 from Creative biogene
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Human UGT2B7 siRNA - orb265537 from Biorbyt
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UGT2B7 shRNA Plasmid (Human) - CHH5035 from Cohesion Biosciences
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UGT2B7 miRNA 3'UTR clone - MiUTR3H-03122 from Creative biogene
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