Gene Symbol | CABYR |
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Entrez Gene | 26256 |
Alt Symbol | CABYRa, CABYRc, CABYRc/d, CABYRe, CBP86, CT88, FSP-2, FSP2 |
Species | Human |
Gene Type | protein-coding |
Description | calcium binding tyrosine-(Y)-phosphorylation regulated |
Other Description | calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)|calcium-binding protein 86|calcium-binding tyrosine phosphorylation-regulated protein|calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)|cancer/testis antigen 88|fibrousheathin 2|fibrousheathin II|fibrousheathin-2|testis-specific calcium-binding protein CBP86 |
Swissprots | Q9HAY4 Q9HCY9 B2R857 Q9HAY3 Q8WXW5 Q9HAY5 O75952 |
Accessions | EAX01174 EAX01175 EAX01176 EAX01177 EAX01178 EAX01179 O75952 AF088868 AAC35373 AF295037 AAG17889 AF295038 AAG17890 AF295039 AAG17891 AF329634 AAL56051 AK225858 AK301889 BAG63320 AK313243 BAG36054 AY007205 AAG01891 BC011996 AAH11996 DB055487 HM594163 HM594164 ADK33596 HM594165 ADK33597 HM594166 ADK33598 HM594167 ADK33599 HM594168 ADK33600 HM594169 ADK33601 HQ448220 ADQ32700 HQ659768 ADX30691 HY051562 XM_005258245 XP_005258302 XM_005258246 XP_005258303 XM_005258247 XP_005258304 XM_011525922 XP_011524224 NM_001308231 NP_001295160 NM_012189 NP_036321 NM_138643 NP_619584 NM_138644 NP_619585 NM_153768 NP_722452 NM_153769 NP_722453 NM_153770 NP_722454 |
Function | May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium. |
Subcellular Location | Isoform 3: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic. |
Tissue Specificity | Expressed in elongating spermatids and spermatozoa (at protein level). Isoform 1 is expressed in testis. Isoform 3 and isoform 5 are also expressed in brain, pancreas and numerous brain tumors. {ECO:0000269|PubMed:11820818, ECO:0000269|PubMed:15752768, ECO:0000269|PubMed:16139264}. |
Human CABYR full length protein - ab161943 from Abcam
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Recombinant Human CABYR Protein - H00026256-P01 from Novus Biologicals
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CABYR peptide - orb218475 from Biorbyt
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CBP86 Blocking Peptide - abx063806 from Abbexa
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CABYR - H00026256-P01-10 from Acris Antibodies
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CABYR - H00026256-P01-25 from Acris Antibodies
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CABYR fusion protein - Ag3012 from Proteintech Group
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Recombinant Human CA - CA-1075H from Creative Biomart
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CBP86 Blocking Peptide - CBP2612 from Cohesion Biosciences
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Recombinant Human Calcium-binding tyrosine phosphorylation-regulated protein(CAB - CSB-YP004393HU CSB-EP004393HU CSB-BP004393HU CSB-MP004393HU from Cusabio
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CABYR (transcript variant 1) - TP314772 from Acris Antibodies
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Calcium-binding tyrosine phosphorylation-regulated protein (CABYR), Recombinant Protein - MBS1231946 from MyBioSource
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CABYR Recombinant Protein Antigen - NBP2-14430PEP from Novus Biologicals
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CABYR Recombinant Protein Antigen - NBP2-14429PEP from Novus Biologicals
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