Gene Symbol | TMEM79 |
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Entrez Gene | 84283 |
Alt Symbol | MATT |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 79 |
Other Description | mattrin |
Swissprots | D3DVB8 Q9BSE2 B2RE22 |
Accessions | EAW52970 EAW52971 EAW52972 Q9BSE2 AK056816 BAB71290 AK122634 AK315767 BAG38119 BC005094 AAH05094 BF448444 DA678865 DA880152 HQ447329 ADQ31815 NM_032323 NP_115699 NR_026678 |
Function | Contributes to the epidermal integrity and skin barrier function. Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial cell formation (By similarity). {ECO:0000250}. |
Subcellular Location | Lysosome {ECO:0000250}. Golgi apparatus, trans-Golgi network {ECO:0000250}. Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}. Note=Colocalized with TGOLN2 in the trans-Golgi network. Colocalized with LAMP1 in the lysosome (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed in the epidermis of the skin. Expressed in epithelial cells of the outermost layer of the stratum granulosum (SG) and hair follicles (at protein level). {ECO:0000269|PubMed:24060273, ECO:0000269|PubMed:24084074}. |
TMEM79 CRISPR/Cas9 KO Plasmid (h) - sc-413611 from Santa Cruz Biotechnology
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TMEM79 HDR Plasmid (h) - sc-413611-HDR from Santa Cruz Biotechnology
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TMEM79 Double Nickase Plasmid (h) - sc-413611-NIC from Santa Cruz Biotechnology
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TMEM79 Double Nickase Plasmid (h2) - sc-413611-NIC-2 from Santa Cruz Biotechnology
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TMEM79 CRISPR Activation Plasmid (h) - sc-413611-ACT from Santa Cruz Biotechnology
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TMEM79 CRISPR Activation Plasmid (h2) - sc-413611-ACT-2 from Santa Cruz Biotechnology
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TMEM79 Lentiviral Activation Particles (h) - sc-413611-LAC from Santa Cruz Biotechnology
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TMEM79 Lentiviral Activation Particles (h2) - sc-413611-LAC-2 from Santa Cruz Biotechnology
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TMEM79 siRNA (h) - sc-78662 from Santa Cruz Biotechnology
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TMEM79 shRNA Plasmid (h) - sc-78662-SH from Santa Cruz Biotechnology
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TMEM79 shRNA (h) Lentiviral Particles - sc-78662-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU133801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21666 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21666 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07202 from Sigma-Aldrich
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TMEM79 siRNA (Human) - CRJ3408 from Cohesion Biosciences
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TMEM79 - MBS8211471 from MyBioSource
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shRNA set against Human TMEM79 (NM_032323.2) - SHH430964 from Creative biogene
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Human TMEM79 siRNA - orb273909 from Biorbyt
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TMEM79 shRNA Plasmid (Human) - CHJ3408 from Cohesion Biosciences
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TMEM79 miRNA 3'UTR clone - MiUTR3H-16368 from Creative biogene
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