| Gene Symbol | PTPN20 |
|---|---|
| Entrez Gene | 26095 |
| Alt Symbol | CT126, PTPN20A, PTPN20B, bA142I17.1, bA42B19.1, hPTPN20 |
| Species | Human |
| Gene Type | protein-coding |
| Description | protein tyrosine phosphatase, non-receptor type 20 |
| Other Description | cancer/testis antigen 126|protein tyrosine phosphatase, non-receptor type 20A|protein tyrosine phosphatase, non-receptor type 20B|tyrosine-protein phosphatase non-receptor type 20 |
| Swissprots | Q5T1G3 Q4JDK8 Q4JDK1 Q4JDL6 Q4JDL0 Q4JDK9 Q5RJ33 B7ZKV3 Q4JDL5 Q4JDL3 Q4JDK5 Q4JDL7 Q4JDK6 Q4JDL4 A6NNH8 Q4JDL8 Q4JDL1 Q4JDG6 |
| Accessions | EAW50662 Q4JDL3 AK309922 AL050040 CAB43248 AY704141 AAW28780 AY704142 AAW28781 AY704143 AAW28782 AY704144 AAW28783 AY704145 AAW28784 AY704146 AAW28785 AY704147 AAW28786 AY704148 AAW28787 AY704149 AAW28788 AY704150 AAW28789 AY704151 AAW28790 AY704152 AAW28791 AY704153 AAW28792 AY704154 AAW28793 AY704155 AAW28794 AY704156 AAW28795 AY704157 AAW28796 AY704158 AAW28797 AY753191 AAW88572 BC036539 BC093750 AAH93750 BC113473 AAI13474 BC141460 AAI41461 BC143394 AAI43395 BC171725 AAI71725 BU567804 BX648913 CR933668 CAI45965 XM_005270315 XP_005270372 XM_011539600 XP_011537902 XM_011539601 XP_011537903 XM_011539602 XP_011537904 XM_011539603 XP_011537905 XM_011539604 XP_011537906 XM_011539605 XP_011537907 XM_011539606 XP_011537908 XM_011539607 XP_011537909 XM_011539608 XP_011537910 XM_011539609 XP_011537911 XM_011539610 XP_011537912 XM_011539611 XP_011537913 XM_011539612 XP_011537914 XM_011539613 XP_011537915 XM_011539614 XP_011537916 XM_011539615 XP_011537917 XM_011539616 XP_011537918 XM_011539617 XP_011537919 XM_011539618 XP_011537920 XM_011539619 XP_011537921 XM_011539620 XP_011537922 XR_945659 XR_945660 NM_001042357 NP_001035816 NM_001042358 NP_001035817 NM_001042359 NP_001035818 NM_001042360 NP_001035819 NM_001042361 NP_001035820 NM_001042362 NP_001035821 NM_001042363 NP_001035822 NM_001042364 NP_001035823 NM_001042365 NP_001035824 NM_015605 NP_056420 NM_001042387 NM_001042389 NM_001042390 NM_001042391 NM_001042392 NM_001042393 NM_001042394 NM_001042395 NM_001042396 NM_001042397 |
| Function | Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:15790311}. Cytoplasm {ECO:0000269|PubMed:15790311}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15790311}. Note=Colocalizes with the microtubule-organizing center and intracellular membrane compartments. |
| Tissue Specificity | Present in many cell lines (at protein level). Widely expressed. {ECO:0000269|PubMed:15790311}. |
PTPN20B CRISPR/Cas9 KO Plasmid (h) - sc-416426 from Santa Cruz Biotechnology
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PTPN20B HDR Plasmid (h) - sc-416426-HDR from Santa Cruz Biotechnology
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PTPN20B Double Nickase Plasmid (h) - sc-416426-NIC from Santa Cruz Biotechnology
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PTPN20B Double Nickase Plasmid (h2) - sc-416426-NIC-2 from Santa Cruz Biotechnology
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PTPN20B CRISPR Activation Plasmid (h) - sc-416426-ACT from Santa Cruz Biotechnology
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PTPN20B CRISPR Activation Plasmid (h2) - sc-416426-ACT-2 from Santa Cruz Biotechnology
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PTPN20B Lentiviral Activation Particles (h) - sc-416426-LAC from Santa Cruz Biotechnology
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PTPN20B Lentiviral Activation Particles (h2) - sc-416426-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU114541 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0750 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP1084 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP1085 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP1086 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0749 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0748 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10100 from Sigma-Aldrich
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PTPN20 siRNA (Human) - CRH8707 from Cohesion Biosciences
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PTPN20 RNAi - H00026095-R03 from Novus Biologicals
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shRNA set against Human Ptpn20 (NM_015605.7) - SHH386504 from Creative biogene
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shRNA set against Human PTPN20B(NM_001042361.3) - SHR152358 from Creative biogene
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shRNA set against Human PTPN20B(NM_001042364.3) - SHR152376 from Creative biogene
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shRNA set against Human PTPN20B(NM_001042359.2) - SHR152394 from Creative biogene
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shRNA set against Human PTPN20B(NM_001042358.3) - SHR152412 from Creative biogene
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shRNA set against Human PTPN20B(NM_001042365.2) - SHR152430 from Creative biogene
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shRNA set against Human PTPN20B(NM_001042360.2) - SHR152448 from Creative biogene
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