Gene Symbol |
TF
|
Entrez Gene |
100009267
|
Alt Symbol |
TRF
|
Species |
Rabbit
|
Gene Type |
protein-coding
|
Description |
transferrin
|
Other Description |
beta-1 metal-binding globulin|liver transferrin|serotransferrin|siderophilin
|
Swissprots |
P19134 O46514
|
Accessions |
AAB94136 P19134 X58533 CAA41424 NM_001101694 NP_001095164
|
Function |
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Expressed by the liver and secreted in plasma.
|
Top Pathways |
Mineral absorption
|