| Gene Symbol |
MBIP
|
| Entrez Gene |
51562
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MAP3K12 binding inhibitory protein 1
|
| Other Description |
MAP3K12-binding inhibitory protein 1|MAPK upstream kinase-binding inhibitory protein|MUK-binding inhibitory protein
|
| Swissprots |
Q9BS93 Q86TZ2 Q9NZE1 Q96AS5 Q9NS73
|
| Accessions |
EAW65862 EAW65863 EAW65864 EAW65865 Q9NS73 AA761503 AB038523 BAA94083 AF208857 AAF64271 AK293473 BAG56966 AK315290 BAG37697 BC005197 AAH05197 BC016821 AAH16821 BX248287 CAD62615 HQ447190 ADQ31677 XM_005267754 XP_005267811 XM_005267755 XP_005267812 XM_005267756 XP_005267813 XM_011536833 XP_011535135 NM_001144891 NP_001138363 NM_001308110 NP_001295039 NM_016586 NP_057670
|
| Function |
Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. {ECO:0000269|PubMed:19103755}.
|
| Subcellular Location |
Nucleus. Cytoplasm. Note=Shows a cytoplasmic localization when coexpressed with MAP3K12.
|
| Tissue Specificity |
Ubiquitous. High expression seen in the heart and lung.
|