Gene Symbol | FBXO42 |
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Entrez Gene | 54455 |
Alt Symbol | Fbx42, JFK |
Species | Human |
Gene Type | protein-coding |
Description | F-box protein 42 |
Other Description | F-box only protein 42|just one F-box and Kelch domain-containing protein |
Swissprots | Q8N3N4 Q9P2L4 B3KP30 Q86XI0 Q8N5F8 Q6P3S6 Q9BRM0 Q5TEU8 |
Accessions | EAW51774 EAW51775 Q6P3S6 AB037753 BAA92570 AK025059 AK055598 BAG51542 AK310671 AL833207 AL833874 CAD38731 AW449773 BC006174 AAH06174 BC032439 AAH32439 BC043410 AAH43410 BC047296 BC063864 AAH63864 DA488838 HY007337 XM_006710698 XP_006710761 NM_018994 NP_061867 |
Function | Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation. {ECO:0000269|PubMed:19509332}. |
FBXO42 CRISPR/Cas9 KO Plasmid (h) - sc-409573 from Santa Cruz Biotechnology
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FBXO42 HDR Plasmid (h) - sc-409573-HDR from Santa Cruz Biotechnology
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FBXO42 Double Nickase Plasmid (h) - sc-409573-NIC from Santa Cruz Biotechnology
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FBXO42 Double Nickase Plasmid (h2) - sc-409573-NIC-2 from Santa Cruz Biotechnology
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FBXO42 CRISPR Activation Plasmid (h) - sc-409573-ACT from Santa Cruz Biotechnology
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FBXO42 CRISPR Activation Plasmid (h2) - sc-409573-ACT-2 from Santa Cruz Biotechnology
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FBXO42 Lentiviral Activation Particles (h) - sc-409573-LAC from Santa Cruz Biotechnology
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FBXO42 Lentiviral Activation Particles (h2) - sc-409573-LAC-2 from Santa Cruz Biotechnology
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FBXO42 siRNA (h) - sc-78739 from Santa Cruz Biotechnology
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FBXO42 shRNA Plasmid (h) - sc-78739-SH from Santa Cruz Biotechnology
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FBXO42 shRNA (h) Lentiviral Particles - sc-78739-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8558 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8558 from Sigma-Aldrich
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FBXO42 siRNA (Human) - CRJ0064 from Cohesion Biosciences
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FBXO42 RNAi - H00054455-R01 from Novus Biologicals
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FBXO42 - MBS829525 from MyBioSource
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shRNA set against Human FBXO42 (NM_018994.1) - SHH293317 from Creative biogene
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Human FBXO42 siRNA - orb270565 from Biorbyt
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FBXO42 shRNA Plasmid (Human) - CHJ0064 from Cohesion Biosciences
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FBXO42 miRNA 3'UTR clone - MiUTR1H-03562 from Creative biogene
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