Gene Symbol | BMP2 |
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Entrez Gene | 650 |
Alt Symbol | BDA2, BMP2A |
Species | Human |
Gene Type | protein-coding |
Description | bone morphogenetic protein 2 |
Other Description | BMP-2A|bone morphogenetic protein 2A |
Swissprots | P12643 |
Accessions | AAF21646 ACV32585 ACV32586 ACV32587 ACV32588 ACV32589 ACV32590 ACV32591 ACV32592 ACV32593 ACV32594 ACV32595 ACV32596 CBY84970 EAX10386 EAX10387 P12643 BC069214 BC140325 AAI40326 BC148689 AAI48690 EU832168 ACE87518 EU832262 ACE86832 KC294426 AGG86667 KF250425 AGW22219 M22489 AAA51834 XM_011529323 XP_011527625 NM_001200 NP_001191 |
Function | Induces cartilage and bone formation. |
Subcellular Location | Secreted. |
Tissue Specificity | Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine. |
Top Pathways | Cytokine-cytokine receptor interaction, Hedgehog signaling pathway, TGF-beta signaling pathway, Basal cell carcinoma, Hippo signaling pathway |
BMP-2 CRISPR/Cas9 KO Plasmid (h) - sc-400514 from Santa Cruz Biotechnology
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BMP-2 HDR Plasmid (h) - sc-400514-HDR from Santa Cruz Biotechnology
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BMP-2 Double Nickase Plasmid (h) - sc-400514-NIC from Santa Cruz Biotechnology
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BMP-2 Double Nickase Plasmid (h2) - sc-400514-NIC-2 from Santa Cruz Biotechnology
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BMP-2 CRISPR Activation Plasmid (h) - sc-400514-ACT from Santa Cruz Biotechnology
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BMP-2 CRISPR Activation Plasmid (h2) - sc-400514-ACT-2 from Santa Cruz Biotechnology
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BMP-2 Lentiviral Activation Particles (h) - sc-400514-LAC from Santa Cruz Biotechnology
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BMP-2 Lentiviral Activation Particles (h2) - sc-400514-LAC-2 from Santa Cruz Biotechnology
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BMP-2 siRNA (h) - sc-39738 from Santa Cruz Biotechnology
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BMP-2 shRNA Plasmid (h) - sc-39738-SH from Santa Cruz Biotechnology
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BMP-2 shRNA (h) Lentiviral Particles - sc-39738-V from Santa Cruz Biotechnology
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BMP-2 siRNA (h2) - sc-270025 from Santa Cruz Biotechnology
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BMP-2 shRNA Plasmid (h2) - sc-270025-SH from Santa Cruz Biotechnology
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BMP-2 shRNA (h2) Lentiviral Particles - sc-270025-V from Santa Cruz Biotechnology
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BMP-2 RNAi - H00000650-R01 from Novus Biologicals
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MISSION® esiRNA - EHU013931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4000 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4000 from Sigma-Aldrich
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BMP2 siRNA (Human) - CRH0445 from Cohesion Biosciences
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BMP2 - MBS828594 from MyBioSource
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shRNA set against Human BMP2 (NM_001200.2) - SHH247034 from Creative biogene
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shRNA set against Human BMP2(NM_001200.2) - SHG101689 from Creative biogene
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BMP-2 CRISPR/Cas9 KO Plasmid (h2) - sc-400514-KO-2 from Santa Cruz Biotechnology
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BMP-2 HDR Plasmid (h2) - sc-400514-HDR-2 from Santa Cruz Biotechnology
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Human BMP2 siRNA - orb260947 from Biorbyt
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