Gene Symbol |
SLC39A2
|
Entrez Gene |
29986
|
Alt Symbol |
6A1, ETI-1, ZIP-2, ZIP2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 39 (zinc transporter), member 2
|
Other Description |
Zrt- and Irt-like protein 2|solute carrier family 39 member 2|zinc transporter ZIP2|zinc uptake transporter 2
|
Swissprots |
Q4V9S4 Q4QQJ1 Q9UD20 G3V5X2 B2RC76 Q96JT6 Q9NP94
|
Accessions |
EAW66431 Q9NP94 AF186081 AAF35832 AI382710 AK314974 BAG37473 AY029483 AAK40258 BC096723 AAH96723 BC098254 AAH98254 BC098274 BC110057 AAI10058 BP359281 CN306082 D83039 BAA94313 DA871745 NM_001256588 NP_001243517 NM_014579 NP_055394
|
Function |
Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Expressed only in prostate and uterine epithelial cells.
|