| Gene Symbol | SNTG1 |
|---|---|
| Entrez Gene | 54212 |
| Alt Symbol | G1SYN, SYN4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | syntrophin, gamma 1 |
| Other Description | gamma-1-syntrophin|gamma1-syntrophin|syntrophin 4|syntrophin-4 |
| Swissprots | Q9NY98 Q2M3Q0 Q9NSN8 |
| Accessions | CAD35041 EAW86704 EAW86705 EAW86706 Q9NSN8 AJ003030 CAB92968 AK314084 BAG36781 AL161971 CAB82311 AM393671 CAL38547 BC075072 AAH75072 BC104829 AAI04830 BC143695 DA237404 DN995011 XM_006716456 XP_006716519 XM_011517545 XP_011515847 XM_011517546 XP_011515848 XM_011517547 XP_011515849 XM_011517548 XP_011515850 XM_011517550 XP_011515852 NM_001287813 NP_001274742 NM_001287814 NP_001274743 NM_018967 NP_061840 |
| Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity). May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation. {ECO:0000250}. |
| Subcellular Location | Cytoplasm, cytoskeleton. Nucleus. Note=Mainly cytoplasmic and weakly nuclear. |
| Tissue Specificity | Brain specific. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. No expression in muscle cells. {ECO:0000269|PubMed:10747910}. |
γ1-Syntrophin CRISPR/Cas9 KO Plasmid (h) - sc-409959 from Santa Cruz Biotechnology
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γ1-Syntrophin HDR Plasmid (h) - sc-409959-HDR from Santa Cruz Biotechnology
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γ1-Syntrophin Double Nickase Plasmid (h) - sc-409959-NIC from Santa Cruz Biotechnology
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γ1-Syntrophin Double Nickase Plasmid (h2) - sc-409959-NIC-2 from Santa Cruz Biotechnology
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γ1-Syntrophin CRISPR Activation Plasmid (h) - sc-409959-ACT from Santa Cruz Biotechnology
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γ1-Syntrophin CRISPR Activation Plasmid (h2) - sc-409959-ACT-2 from Santa Cruz Biotechnology
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γ1-Syntrophin Lentiviral Activation Particles (h) - sc-409959-LAC from Santa Cruz Biotechnology
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γ1-Syntrophin Lentiviral Activation Particles (h2) - sc-409959-LAC-2 from Santa Cruz Biotechnology
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γ1-Syntrophin siRNA (h) - sc-43441 from Santa Cruz Biotechnology
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γ1-Syntrophin shRNA Plasmid (h) - sc-43441-SH from Santa Cruz Biotechnology
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γ1-Syntrophin shRNA (h) Lentiviral Particles - sc-43441-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU088951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20281 from Sigma-Aldrich
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SNTG1 siRNA (Human) - CRJ0034 from Cohesion Biosciences
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SNTG1 - MBS8232133 from MyBioSource
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shRNA set against Human SNTG1 (NM_018967.2) - SHH414480 from Creative biogene
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shRNA set against Human SNTG1(NM_018967.2) - SHL022692 from Creative biogene
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Human SNTG1 siRNA - orb270535 from Biorbyt
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SNTG1 shRNA Plasmid (Human) - CHJ0034 from Cohesion Biosciences
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SNTG1 miRNA 3'UTR clone - MiUTR1H-09706 from Creative biogene
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