Gene Symbol | GLRX5 |
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Entrez Gene | 51218 |
Alt Symbol | C14orf87, FLB4739, GRX5, PR01238, PRO1238, PRSA |
Species | Human |
Gene Type | protein-coding |
Description | glutaredoxin 5 |
Other Description | glutaredoxin 5 homolog|glutaredoxin-related protein 5, mitochondrial|monothiol glutaredoxin-5 |
Swissprots | Q86WY3 Q0X088 Q86SX6 Q8IZ54 Q3YML0 |
Accessions | CAJ42814 EAW81606 EAW81607 Q86SX6 AB223038 BAF02301 AF113691 AAF29586 AI089763 BC023528 AAH23528 BC047680 AAH47680 BC071690 BC105275 BI259789 BI834047 BX248075 CAD62364 DQ083331 AAZ30731 NM_016417 NP_057501 |
Function | Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1. |
Subcellular Location | Mitochondrion {ECO:0000250}. |
Grx5 CRISPR/Cas9 KO Plasmid (h) - sc-409931 from Santa Cruz Biotechnology
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Grx5 HDR Plasmid (h) - sc-409931-HDR from Santa Cruz Biotechnology
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Grx5 Double Nickase Plasmid (h) - sc-409931-NIC from Santa Cruz Biotechnology
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Grx5 Double Nickase Plasmid (h2) - sc-409931-NIC-2 from Santa Cruz Biotechnology
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Grx5 CRISPR Activation Plasmid (h) - sc-409931-ACT from Santa Cruz Biotechnology
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Grx5 CRISPR Activation Plasmid (h2) - sc-409931-ACT-2 from Santa Cruz Biotechnology
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Grx5 Lentiviral Activation Particles (h) - sc-409931-LAC from Santa Cruz Biotechnology
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Grx5 Lentiviral Activation Particles (h2) - sc-409931-LAC-2 from Santa Cruz Biotechnology
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Grx5 siRNA (h) - sc-61857 from Santa Cruz Biotechnology
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Grx5 shRNA Plasmid (h) - sc-61857-SH from Santa Cruz Biotechnology
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Grx5 shRNA (h) Lentiviral Particles - sc-61857-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU045021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9360 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9360 from Sigma-Aldrich
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GLRX5 siRNA (Human) - CRH9613 from Cohesion Biosciences
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GLRX5 - MBS8234713 from MyBioSource
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shRNA set against Human GLRX5 (NM_016417.2) - SHH302026 from Creative biogene
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shRNA set against Human GLRX5(NM_016417.2) - SHH087905 from Creative biogene
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Human GLRX5 siRNA - orb270115 from Biorbyt
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GLRX5 shRNA Plasmid (Human) - CHH9613 from Cohesion Biosciences
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GLRX5 miRNA 3'UTR clone - MiUTR1H-04074 from Creative biogene
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